Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2011, vol. 17, book 1
Subject Collection: Medicine
Online date: October 7, 2011
J of IMAB 2011; 17(1):152-153
HIGH PREVALENCE OF HBsAg CARRIERS IN A SPECIFIC COMMUNITY IN BULGARIA
Zahariy Krastev1, Ivan Stoev2, Deian Jelev1, Aneta Ivanova1, Krasimir Antonov1, Luydmila Mateva1
1) Clinic of Gastroenterology, St. Ivan Rilsky University Hospital, Sofia, Bulgaria; 2) General Practitioner in village of Ablaniza, Bulgaria
Objective: HBV-infection is intermediate-endemic in Bulgaria. There is a trend for decreasing of HBsAg-carrier rate in the last decades, but prevalence remains higher in some specific ethnic communities. Current data regarding high-endemic sources of HBV-infection are limited.
Methods: HBsAg and anti-HCV were tested in 677 subjects from a specific ethnical community: 413 adults and 264 adolescents, covered by the National Program for HBV-vaccination of all newborns.
Results: Thirty-two of adults (7,7%) were HBsAg-positive. The observed HBsAg-carrier rate was more than three folds higher than general Bulgarian population. In contrast only 2/264 (0.7%) of adolescents were HBsAg-positive. They both were born from HBsAg-positive mothers. Anti-HCV-positive subjects have been found neither among adults nor among adolescents.
Conclusion: Our results confirmed existence of separate high-endemic sources of HBV infection in Bulgaria. HBV vaccination program is highly effective even in such specific subgroups and resulted in marked decrease of HBsAg-carrier rate among adolescents.
Key words: HBV epidemiology, HBsAg prevalence, ethnical groups, HBV vaccination .
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Please cite this article as: Krastev Z, Stoev I, Jelev D, Ivanova A, Antonov K, Mateva L. High prevalence of HBsAg carriers in a specific community in Bulgaria. J of IMAB 2011; 17(1):152-153. doi: 10.5272/jimab.2011171.152
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