PREMEDICATION PROTOCOLS IN DENTAL PRACTICE IN ALLERGIC PATIENTS

The problem with choosing a suitable pre-medication protocols before local anesthesia in dentistry in allergic patients is always discussed, as in the dental practice different schemes are already proven (3, 5). The propose of this communication is to share the experience on those pre-medication schemes in allergic patients during and outside pollen season. INTRODUCTION To be considered safe, dental treatment (including usually local anaesthesia) needs some precautions which sometimes are neglected by dental practitioners. Obtaining a credible medical history is the first step, especially in allergic patients. An examination by an allergist and skin testing is needed. Based on this information a premedication


INTRODUCTION.
Pain control is a serious problem in medicine.Elimination of pain is essential for a favourable outcome of a treatment.In dental medicine, it is of paramount importance to know as much as possible about how to control pain because the disorders in this field have usually a very painful course due to the dense net of nerve receptors in the maxillofacial region.That is why research in the field of dental anesthesiology is never ceasing globally giving as a result new preparations designed for local anesthesia and development of new methods to administer the various types of anesthesia.
In historical perspectives, the constant search for optimisation of local anesthesia leads to constant synthesis of new drugs designed to improve the efficiency of the anesthetic and reduce at the same time the side effects that were characteristic of previous generations of local anesthetics.It has been found that a combination of a local anesthesia preparation and a vasoconstrictive agent of the group of cathecholamines has a particular good effect.As a result the amount of drug used for anesthesia is reduced considerably. 13But local anesthetics have some side effects that are especially pronounced in patients with heart diseases.There have been a number of studies on the drugs used for local anesthesia in these patients.These studies aim at finding what the effects of anesthetics and corrigents are and at developing algorithms for their use and achievement of optimal painless treatment.
A primary requirement in modern dental treatment is that it should be painless. 1,8 he efficiency of the different types of anesthesia has been well researched, but the problem arising from the use of various anesthetics in patients with heart diseases is still controversial.To achieve an optimal anesthetic effect it is important to select very precisely the type of anesthetic, determine its dose and study very carefully the side effects it may have on the cardiovascular system of patients.There are increasingly frequent reports in the relevant literature of the finding that adding just a little amount of corrigent to the anesthetic does not exert a negative effect on certain cardiovascular diseases, increasing considerably the efficiency of anesthesia at the same time. 3,5,6,7,14 Theim of the present study was to introduce Holter cardiac monitoring to find what effect vasoconstrictors have on modern local anesthetics in patients with specific heart diseases.

MATERIAL AND METHODS
The study included 18 patients planning to have dental surgery; the patients were diagnosed with the following heart diseases: previous myocardial infarction, ischemic heart disease, hypertension and stable stenocardia.The status of the studied patients was ascertained by their medical history and cardiologic tests (coronarography and exercise tolerance test).The principal method used in the study is based on 24-hour recording of ECG using a Holter monitor.The purpose was to use a Holter ECG to establish changes in the cardiac activity during and after anesthesia was administered and the surgery performed.Any pathological changes in the cardiovascular system were detected using the changes in the ST segment of the ECG.Each patient was fitted with an ambulatory electrocardiography device (Holter monitor) in advance; the device was turned on to record the ECG of patients immediately before anesthesia was administered. 2,4 his was the starting point in the subsequent analysis of the cardiogram.The blood pressure and pulse rate were measured three times prior to, during and after the surgery.We used artcaine as a relatively new preparation.

RESULTS AND DISCUSSION
The main parameter analysed in this technique is the depression of the ST segment on cardiogram.It is an indicator of a possible ischemic disorder or necrosis in the cardiac muscle.The cardiograms were analysed after completion of the surgical procedures to find any changes in this parameter.We analysed the changes in blood pressure and heart rate.The analysis found no significant depression of the ST segment (greater than 1 mm).The blood pressure and heart rate also showed no pathological deviations from baseline values.The anesthesia given to the patients was at a depth at which they felt no pain during surgery.No other events related to the underlying disorders were found.

Picture 2 .
Leads positioning Picture 1. Holder monitor Picture 3. Changes in the ST segment 11,12