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Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2012, vol. 18, book 1
Subject Collection: Medicine
Page: 216 - 219
DOI: 10.5272/jimab.2012181.216
Published online: 17 February 2012
J of IMAB 2012; 18(1):216-219
Antibiotic susceptibility of Salmonella spp.: a comparison of two surveys with a 5 years interval
Gordana Mijović1, Bogdanka Andrić2, Dragica Terzić2, Milena Lopičić1, Brankica Dupanović2
1 Institute of public health, Podgorica
2 Clinic for infectious diseases, Clinical center of Montenegro, Podgorica, Montenegro.
ABSTRACT:
Salmonella infections are one of the major global public health problems. During the last decade, antibiotic resistance and multiresistance of Salmonella spp. have increased a great deal, especially in developing countries with an increased and indiscriminate use of antibiotics in the treatment of humans and animals.
This study aims to investigate and compare antimicrobial susceptibility patterns of Salmonella during 2005 and 2010.
A total of 186 Salmonella strain during 2005 and 140 Salmonella strain during 2010 were isolated from stool specimens using standard methods. The isolates were confirmed as Salmonella by using a battery of biochemical reactions. Specific antisera were used for serologic characterization of Salmonella strain. Antimicrobial susceptibility testing was performed by standard disk diffusion method using ampicillin, trimethoprim-sulfamethoxasole, ceftriaxon, chloramphenicol, nalidixic acid and ciprofloxacin.
One hundred eighty (96.8%) of 186 isolated Salmonella strains in 2005, and 133 (95%) of 140 isolated Salmonella strain in 2010 are recognized as Salmonella Enteritidis. Sensitivity of Salmonella isolates during 2005 and 2010 were 91.9% and 92.9% to ampicillin, 95.7% and 97.1% to trimethoprim-sulfamethoxasole, 99.5% and 100% to chloramphenicol, 99.5% and 100% to ciprofloxacin, 98.9% and 97.1% to ceftriaxon, 73.1% and 95.7% to nalidixic acid, respectively.
Sensitivity of Salmonella isolates to all tested antimicrobial agents except to ceftriaxon was been slightly improved over testing period. Resistance rate to ceftriaxon was higher in 2010 than in 2005, and this fact deserves attention. Significantly increase susceptibility rate to nalidixic acid was observed between the two surveys.
Key words: nontyphoid, salmonella, antibiotic susceptibility.
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Please cite this article as: Mijović G, Andrić B, Terzić D, Lopičić M, Dupanović B. Antibiotic susceptibility of Salmonella spp.: a comparison of two surveys with a 5 years interval. J of IMAB. 2012; 18(1):216-219. doi: 10.5272/jimab.2012181.216
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Accepted for publication: 09 December 2011
Issue published online: 17 February 2012