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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Year: 2013, vol. 19, issue 2
Subject Collection: Oral and Dental Medicine
Pages: 298-304
DOI: 10.5272/jimab.2013192.298
Published online: 04 June 2013
J of IMAB 2013; 19(2):298-304
DENTAL MANAGEMENT AND BLEEDING COMPLICATIONS OF PATIENTS ON LONG-TERM ORAL ANTIPLATELET THERAPY. REVIEW OF EXISTING STUDIES AND GUIDELINES.
Atanaska Dinkova1
, Donka G. Kirova1, Delyan Delev2
1) Department of Oral surgery, Faculty of Dental Medicine, 2) Department of Pharmacology and Clinical Pharmacology, Medical University Plovdiv, Bulgaria.
ABSTRACT:
Antiplatelet drugs are currently widely used in primary and especially secondary prevention of cardiovascular events.
Dental management of patients on antiplatelet therapy is still not clearly defined: the discontinuation of antiplatelet therapy increases the risk of thrombotic complications, whereas uninterrupted antiplatelet therapy is assumed to increase the bleeding complications after dental surgical procedures.
The aim of this article is to review the main antiplatelet drugs used for long-term oral antiplatelet therapy, the laboratory methods for evaluating effectiveness of this therapy, to identify the studies and guidelines available for dental management of patients on antiplatelet drugs and to summarize their conclusions and recommendations.The methodology used through the research for the literature review includes the following sources: Medscape, Pubmed - Medline database, Science Direct, and EBSCO host, the data base of Medical University Plovdiv and specialised published books in general medicine and dentistry.
Key words: hemostasis alteration, blood coagulation disorders, antiplatelet drugs, aspirin, clopidogrel, new antiplatelet agents, dental management antiplatelet, oral surgery antiplatelet, thrombosis, fibrin sealants, tranexamic acid.
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Please cite this article as:
Dinkova A, Kirova DG, Delev D. Dental management and bleeding complications of patients on long-term oral antiplatelet therapy. Review of existing studies and guidelines. J of IMAB. 2013; 19(2):298-304. doi: 10.5272/jimab.2013192.298
Correspondence to: Atanaska Dinkova, DMD, DDS; Department of Oral surgery, Faculty of Dental Medicine, Medical University Plovdiv, Bulgaria;
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Received: 20 March 2013
Published: 04 June 2013