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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2014, vol. 20, issue 2
Subject Collection: Medicine
Pages: 489-494
DOI: 10.5272/jimab.2014202.489
Published online: 28 March 2014
J of IMAB 2014 Jan-Jun;20(2):489-494
CLINICAL AND NEUROIMAGING STUDIES IN PATIENTS WITH ACUTE SPONTANEOUS INTRACEREBRAL HEMORRHAGE.
Мaya P. Danovska1 
, Margarita L. Alexandrova2, Nachko I. Totsev3, Irena I. Gencheva4, Plamen G. Stoev1.
1) Neurology Clinic, University Hospital, Medical University Pleven, Bulgaria
2) Department of Biophysics, Medical University – Pleven, Bulgaria
3) Department of Neuroimaging Studies, University Hospital – Pleven, Bulgaria
4) Medical Diagnostic Clinical Laboratory, University Hospital – Pleven, Bulgaria.
ABSTRACT:
Objective: To define the prognostic value of clinical and neuroimaging parameters on the 30-th day mortality and clinical outcome after spontaneous intracerebral hemorrhage (sICH).
Materials and methods: we examined 88 patients with sICH admitted to Neurology Clinic, UMHAT Pleven within 48 hours after clinical symptoms onset. Glasgow Coma Scale (GCS) score was used to assess the primary stroke severity; neurological deficit on admission was assessed by National Institute of Health Stroke Scale (NIHSS); clinical outcome at discharge was evaluated by modified Rankin Scale (mRS) and by Glasgow Outcome Scale (GOS) on the 30-th day after sICH onset. Hematoma volume was measured by the formula of Kothari: AxBxC/2 in ml. The statistical analysis was performed by SPSS 19.0 and Statgraphics plus 4.1 for Windows.
Results: Initial assessment of primary stroke severity and neurological deficit by GCS и NIHSS, hematoma localization and volume were found strongly correlated with the clinical outcome on the 30-th day after the sICH onset. Age and vascular risk factors did not correlate with the clinical outcome. Male patients had better survival on the 30-th day compared with the female ones.
Discussion: Neurological deficit on admission, hematoma localization and volume were found reliable predictors of the 30-th day clinical outcome that could serve for early stratification of patients and optimal choice of therapeutic approach.
Key words: CT; neurological deficit; sICH; clinical outcome;
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Please cite this article as:
Danovska MP, Alexandrova ML, Totsev NI, Gencheva II, Stoev PG. Clinical and Neuroimaging Studies in Patients with Acute Spontaneous Intracerebral Hemorrhage. J of IMAB. 2014 Jan-Jun;20(2):489-494. doi: 10.5272/jimab.2014202.489.
Correspondence to: Dr. Maya Danovska, Department of Neurology, University Hospital, 8a, Georgi Kochev str., 5800 Pleven, Bulgaria; E-mail: mdanovska@yahoo.com
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Received: 19 December 2013
Published online: 28 March 2014