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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2015, vol. 21, issue 1
Subject Area: Medicine- Pathophysiology
Pages: 718-721
DOI: 10.5272/jimab.2015211.718
Published online:18 March 2015
J of IMAB 2015 Jan-Mar;21(1):718-721
THE EFFECT OF SMOKING ON THE AUTONOMIC HEART REGULATION IN YOUNG "HEALTHY" MALE SMOKERS.
Zdravko Taralov1
, Peter Dimov1, Kiril Terziyski1, Ilcho Ilchev2, Stefan Kostianev1.
1) Department of Pathophysiology, Faculty of Medicine, Medical University of Plovdiv,
2) MHAT Sv. Ivan Rilski, Plovdiv, Bulgaria.
ABSTRACT:
The aim of our study was to compare the autonomic nervous system (ANS) activity between young “healthy” male smokers and non-smokers via the method of heart rate variability (HRV).
Pulse oximetry, blood pressure, time and frequency domain and non-linear HRV parameters were measured in 21 healthy non-smoker males aged 28.0 ± 7.4 (mean±SD) and fourteen “healthy” smoker males aged 28.1±4.3 with 9.2±5.6 pack-years resting in supine position. Smokers were instructed to refrain from smoking at least 2 hours before the test.
There was no difference between smokers and non-smoker, regarding oxygen saturation (96.3±1.6 vs 96.8±1.2% p=0.330) and blood pressure (117.4±9.4/75.5±7.1 vs 119.5±6.4/77.2±7.1 mmHg p=0.312) but smokers had higher heart rate at rest (76.3±14.2 vs 65.2±9.0 b/min p=0.008). Smokers had decreased standard deviation of normal-to-normal interval (SDNN) (40.3±16.3 vs 62.0±32.1 ms p=0.013) and root mean square of the successive differences (RMSSD) (24.9±12.5 vs 59.3±32.8 ms <0.001). Frequency domain analysis showed that smokers had decreased total power (lnTP) (7.0±0.8 vs 7.7±1.1 ms2 p=0.046), but higher LF/HF index (2.3±0.9 vs 1.4±0.8 p=0.004). Sample entropy was higher in non-smokers (1.4±0.3 vs 1.6±0.2 p=0.049).
Cigarette smoking altered autonomic nervous function measured by HRV in young “healthy” males in the absence of subjective clinical signs or symptoms. The method may be applied in the clinical practice to detect early changes in the ANS activity..
Key words: smoking, heart rate variability, autonomic nervous system,
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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Taralov Z, Dimov P, Terziyski K, Ilchev I, Kostianev S. The Effect of Smoking on the Autonomic Heart Regulation in Young “Healthy” Male Smokers. J of IMAB. 2015 Jan-Mar;21(1):718-721. doi: http://dx.doi.org/10.5272/jimab.2015211.718
Correspondence to: Dr Zdravko Taralov, Department of Pathophysiology, Faculty of Medicine, Medical University of Plovdiv, 15A, Vassil Aprilov Blvd., 4002 Plovdiv, Bulgaria; E-mail: ztaralov@pathophysiology.info
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Received: 19 January 2015
Published online: 18 March 2015