Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312-773X (Online)
Issue: 2017, vol. 23, issue 1
Subject Area: Dental Medicine
DOI: 10.5272/jimab.2017231.1510
Published online: 28 March 2017

Original Article

J of IMAB 2017 Jan-Mar;23(1):1510-1515
Natalia Gateva1 ORCID logoCorresponding Autor, Angela Gusiyska2ORCID logo, Pavel Stanimirov3ORCID logo, Ivan Raychev2ORCID logo, Rossitza Kabaktchieva1ORCID logo
1) Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University - Sofia, Bulgaria
2) Department of Conservative Dentistry, Faculty of Dental Medicine, Medical University - Sofia, Bulgaria
3) Department of Oral and Maxillo-Facial Surgery, Faculty of Dental Medicine, Medical University - Sofia, Bulgaria.

A new type of one-step self-etch adhesives classified as "Universal" or "multi-mode" adhesives appeared in recent years. The idea is that these adhesives can be applied simultaneously with both techniques - etch and rinse and with self-etching technique, without compromising the bonding effectiveness. The aim of this study is to evaluate the micro-tensile adhesive bond strength to dentin of permanent teeth achieved after application of Single Bond Universal (3M ESPE) adhesive system used in multi-mode manner. The results of our study show that the use of this universal adhesive system in multi-mode manner will not lead to the same results regarding the achieved bond strength with dentin. The additional etching with 37% phosphoric acid as well as the application of the adhesive in several layers deteriorates the bond strength right after application and after six months storage in artificial saliva medium (SAGF).

Key words: adhesion, durability, micro-tensile bond strength, multi-mode manner, permanent teeth, universal all-in-one adhesive,

- Download FULL TEXT /PDF 511 KB/
Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Gateva N, Gusiyska A, Stanimirov P, Raychev I, Kabaktchieva R. Biodegradation and Dentin Bonding Effectiveness of one “Universal” Self-etch Adhesive Used in Multi-mode Manner. J of IMAB. 2017 Jan-Mar;23(1):1510-1515. DOI: 10.5272/jimab.2017231.1510.

For correspondence: Natalia Gateva, Associate Professor of the Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University - Sofia, Bulgaria; 1, St. Georgi Sofiiski str., 1431 Sofia, Bulgaria; E-mail:

1. Marchesi G, Frassetto A, Mazzoni A, Apolonio F, Diolosа M, Cadenaro M, et al. Adhesive performance of a multi-mode adhesive system: 1-year in vitro study. J Dent. 2014 May; 42(5):603-12. [PubMed] [CrossRef]
2. Peumans M, Kanumilli P, De Munck J, Van Landuyt K, Lambrechts P, Van Meerbeek B. Clinical effectiveness of contemporary adhesives: a systematic review of current clinical trials. Dent Mater 2005 Sep; 21(9):864–81. [PubMed]
3. Van Landuyt KL, Kanumilli P, De Munck J, Peumans M, Lambrechts P, Van Meerbeek B. Bond strength of a mild self-etch adhesive with and without prior acid-etching. J Dent 2006 Jan; 34(1):77-85. [PubMed]
4. Van Meerbeek B, De Munck J, Yoshida Y,  Inoue S, Vargas M, Vijay P et al. Buonocore memorial lecture. Adhesion to enamel and dentin: current status and future challenges. Oper Dent 2003 May-Jun; 28(3):215-35. [PubMed]
5. Boullagguet S, Gysi P, Wataha JC, Ciucchi B, Cattani M, Godin C,  et al. Bond strength of composite to dentin using conventional, one step, and self-etching adhesive systems. J Dent 2001 Jan; 29(1):55–61. [PubMed]
6. Peumans M, De Munck J, Van Landuyt KL, Poitevin A, Lambrechts P, Van Meer- beek B.  Eight-year clinical evaluation of a two-step self-etch adhesive with and without selective enamel etching. Dent Mater 2010 Dec;26(12):1176-1184. [PubMed]
7. Van Meerbeek B, Yoshihara K, Yoshida Y, Mine A, De Munck J, Van Landuyt KL. State of the art of self-etch adhesives. Dental Mater. 2011 Jan; 27(1):17-28. [PubMed]
8. Cardoso MV, Neves AA, Mine A, Coutinho E, Van Landuyt K, De Munck J, et al. Current aspects on bonding effectiveness and stability in adhesive dentistry. Aust Dent J. 2011 Jun;56(Suppl 1):31-44. [PubMed]
9. Ahn J, Jung KH, Son SA, Hur B, Kwon YH, Park JK. Effect of additional etching and ethanol-wet bonding on the dentin bond strength of one-step self-etch adhesives. Restor Dent Endod. 2015 Feb; 40(1):68-74. [PubMed] [CrossRef]
10. Perdigao J, Gerardeli S, Hodges JS. Total-etch versus self-etch adhesives: effect on postoperative sensitivity. J Am Dent Assoc. 2003 Dec;134(12):1621-9. [PubMed]
11. Sabatini C. Effect of phosphoric acid etching on the shear bond strength of two self-etch adhesives. J Appl Oral Sci. 2013 Jan-Feb;21(1):56-62. [PubMed]
12. Carmona V, Lopez S, Munoz C, Briones-Luján MT. Interfacial Morphology and Bond Strength of Self-Etching Adhesives to Primary Dentin with or Without Acid Etching. J Biomed Mater Res Part B: Appl Biomater. 2008 Nov;87(2):499–507. [CrossRef]
13. Pascon FM, Kantovitz KR, Caldo-Teixeira AS, Borges AF, Silva TN, Puppin-Rontani RM, et al. Clinical evaluation of composite and compomer restorations in primary teeth: 24-Month results. J Dent. 2006 Jul;34(6):381–8. [PubMed]
14. De Munck J, Mine A, Poitevin A, Van Ende A, Cardoso MV, Van Landuyt KL, et al. Meta-analytic review of parameters involved in dentin bonding. J Dent Res. 2012 Apr;91(4):351-7. [PubMed]
15. Tay FR, Pashley DH. Have dentin adhesives become too hydrophilic? J Can Dent Assoc. 2003 Dec;69(11):726–31. [PubMed]
16. Tay FR, Pashley DH. Water treeing - a potential mechanism for degradation of dentin adhesives. Am J Dent. 2003 Feb;16(1):6-12. [PubMed]
17. Chersoni S, Suppa P, Grandini S, Goracci C, Monticelli F, Yiu C, et al. In vivo and in vitro permeability of one-step self-etch adhesives. J Dent Res. 2004 Jun;83(6):459-64. [PubMed]
18. De Andrade e Silva SM, Carrilho MR, Marquezini JL, Garcia FC, Manso AP, Alves MC, et al. Effect of an additional hydrophilic versus hydrophobic coat on the quality of dentinal sealing provided by two-step etch-and-rinse adhesives. J Appl Oral Sci. 2009 May-Jun;17(3):184-9. [PubMed]
19. Hashimoto M, Ito S, Tay FR, Svizero NR, Sano H, Kaga M, et al. Fluid movement across the resin-dentin interface during and after bonding. J Dent Res. 2004 Nov; 83(11): 843-8. [PubMed]
20. Tay FR, Frankenberger R, Krejci I, Bouillaguet S, Pashley DH, Carvalho RM, et al. Single-bottle adhesives behave as permeable membranes after polymerization. I. In vivo evidence. J Dent. 2004 Nov;32(8):611-21. [PubMed]
21. Tay FR, Pashley DH, Suh BI, Carvalho RM, Itthagarun A. Single-step adhesives are permeable membranes. J Dent. 2002 Sep-Nov;30(7-8):371–82. [PubMed]
22. Hashimoto M, Ohno H, Sano H, Kaga M, Oguchi H. In vitro degradation of resin-dentin bonds analyzed by microtensile bond test, scanning and transmission electron microscopy. Biomaterials. 2003 Sep;24(21):3795–803. [PubMed]
23. Hashimoto M, Tay FR, Ohno H, Sano H, Kaga M, Yiu C, et al. SEM and TEM analysis of water degradation of human dentinal collagen. J Biomed Mater Res B Appl Biomater. 2003 Jul 15;66(1):287–98. [PubMed]
24. Perdigao J, Geraldeli S. Bonding characteristics of selfetching adhesives to intact versus prepared enamel. J Esthet Restor Dent 2003;15(1):32-41. [PubMed]
25. Sezinando A.: Looking for the ideal adhesive – A review. Rev Port Estomatol Med Dent Cir Maxilofac. 2014; 55(4):194–206.
26. Erickson RL, Barkmeier WW, Latta MA. The role of etching in bonding to enamel: a comparison of self-etching and etch-and-rinse adhesive systems. Dent Mater. 2009 Nov;25(11):1459–67. [PubMed]
27. Tay FR, Pashley DH. Aggressiveness of contemporary self-etching systems I: depth of penetration beyond dentin smear layers. Dent Mater. 2001 Jun;17(4):296–308. [PubMed]
28. Ito S, Tay FR, Hashimoto M, Yoshiyama M, Saito T, Brackett WW, et al. Effects of Multiple Coatings of Two All-in-one Adhesives on Dentin Bonding  J Adhes Dent 2005 Summer;7(2):133-41. [PubMed]
29. Watanabe I, Nakabayashi N, Pashley DH. Bonding to ground dentin by a phenyl-P self-etching primer. J Dent Res. 1994 Jun;73(6):1212–20. [PubMed]
30. Abo T, Uno S, Sano H. Comparison of bonding efficacy of an all-in-one adhesive with a self-etching primer system. Eur J Oral Sci. 2004 Jun;112(3):286-92. [PubMed]
31. Kenshima S, Francci C, Reis A, Loguercio AD, Filho LE. Conditioning effect on dentin, resin tags and hybrid layer of different acidity self-etch adhesives applied to thick and thin smear layer. J Dent. 2006 Nov; 34(10): 775-83. [PubMed]
32. Suyama  Y, Lührs АК, De Munck J, Mine A, Poitevin A, Yamada T et al. Potentiai Smear Layer Interference with Bonding of Self-etching Adhesives to Dentin J Adhes Dent. 2013 Aug; 15(4):317-24. [PubMed]
33. Еliades G, Watts DC, Eliades T. Dental hard tissues and bonding. Springer. 2005; 109-122.
34. Oliveira SS, Marshall SJ, Hilton JF, Marshall GW. Etching kinetics of a self-etching primer. Biomaterials. 2002 Oct;23(20):4105-12. [PubMed]
35. Chen C, Niu LN, Xie H, Zhang ZY, Zhou LQ, Jiao K, et al. Bonding of universal adhesives to dentine - Old wine in new bottles? J Dent. 2015 May;43(5): 525-36. [PubMed]
36. Hanabusa M, Mine A, Kuboki Т, Momoi Y, Van Ende A, Van Meerbeek B, et al. Bonding effectiveness of a new ‘multi-mode’ adhesive to enamel and dentine. J Dent. 2012 Jun;40(6):475-84. [PubMed]
37. Hashimoto M, Sano H, Yoshida E, Hori M, Kaga M, Oguchi H, et al. Effects of multiple adhesive coatings on dentin bonding. Oper Dent. 2004 Jun;29(4):416-23. [CrossRef]
38. Erhardt MC, Cavalcante LM, Pimenta LA. Influence of phosphoric acid pre-treatment on self-etching bond strength. J Esthet Restor Dent. 2004; 16(1):33-40. [PubMed]
39. Gokce K, Aykor A, Ersoy M, Ozel E, Soyman M. Effect of phosphoric acid etching and self-etching primer application methods on dentinal shear bond strength. J Adhes Dent. 2008 Oct;10(5):345-9. [PubMed]
40. Ikeda M, Kurokawa H, Sunada N, Tamura Y, Takimoto M, Murayama R. et al. Influence of previous acid etching on dentin bond strength of self-etch adhesives. J Oral Sci. 2009 Dec;51(4):527-34. [PubMed]
41. Salvio LA, Hopilito VD, Martins AL, de Goes MF. Hybridization quality and bond strength of adhesive systems according to interaction with dentin. Eur J Dent. 2013 Jul;7(3):315-326. [PubMed]
42. Torii Y, Itou K, Nishitani Y, Ishikawa K, Suzuki K. Effect of phosphoric acid etching prior to self-etching primer application on adhesion of resin composite to enamel and dentin. Am J Dent. 2002 Oct;15(5):305-8. [PubMed]
43. Zou Y, Jessop JL, Armstrong SR. In-vitro enzymatic biodegradation of adhesive resin in the hybrid layer. J Biomed Mater Res A. 2010 Jul;94(1):187-192. [PubMed]
44. Perdigao J, Munoz M, Sezinando A, Luque-Martinez IV, Staichak R, Reis A, et al. Immediate adhesive properties to dentin and enamel of a universal adhesive associated with a hydrophobic resin coat. Oper Dent. 2014 Sep; 39(5):489–99. [PubMed]
45. Rosa WL, Piva E, Silva AF. Bond strength of universal adhesives: A systematic review and meta-analysis. J Dent. 2015 Jul;43(7):765-76. [PubMed]
46. Carvalho RM, Chersoni S, Frankenberger R, Pashley DH, ;Prati C, Tay FR. A challenge to the conventional wisdom that simultaneous etching and resin infiltration always occurs in selfetch adhesives. Biomaterials. 2005 Mar; 26(9):1035-42. [PubMed]
47. De Munck J, Van Landuyt K, Peumans M, Poitevin A, Lambrechts P, Braem M, et al. A critical review of the durability of adhesion to tooth tissue: methods and results. J Dent Res. 2005 Feb;84(2):118-32. [PubMed]
48. Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, et al. Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials. 2007 Sep;28(26):3757-85. [PubMed]
49. Taschner M, Nato F, Mazzoni A, Frankenberger R, Krämer N, Di Lenarda R, at al. Role of preliminary etching for one-step self-etch adhesives. Eur J Oral Sci. 2010 Oct;118(5):517-24. [PubMed]
50. Moszner N, Salz U, Zimmermann J. Chemical aspects of selfetching enamel-dentin adhesives: a systematic review. Dent Mater. 2005 Oct;21(10):895-910. [PubMed]
51. Yoshida Y, Nagakane K, Fukuda R, Nakayama Y, Okazaki M, Shintani H, et al. Comparative study on adhesive performance of functional monomers. J Dent Res. 2004 Jun;83(6):454-8. [PubMed]
52. Yoshida Y, Van Meerbeek B, Nakayama Y, Snauwaert J, Hellemans L, Lambrechts P, et al. Evidence of chemical bonding at bio-material-hard tissue interfaces. J Dent Res. 2000 Feb;79(2):709-14. [PubMed].

Received: 23 January 2017
Published online: 28 March 2017

back to Online Journal