head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing
ISSN: 1312-773X (Online)
Issue: 2017, vol. 23, issue 4
Subject Area: Medicine
DOI: 10.5272/jimab.2017234.1718
Published online: 16 October 2017

Original article

J of IMAB 2017 Oct-Dec;23(4):1718-1720
Ivan Dimitrov1 ORCID logo Corresponding Autoremail, Ivan Aleksandrov1 ORCID logo, Borislav Ivanov2 ORCID logo, Ara Kaprelyan3 ORCID logo, Mariana Arnaoudova4 ORCID logo,
1) Department of Nursing, Sliven Affiliate, Medical University - Varna, Bulgaria.
2) Department of Clinical Medical Sciences, Medical University - Varna, Bulgaria.
3) Department of Neurology and Neuroscience, Medical University - Varna, Bulgaria.
4) Department of Psychiatry and Medical Psychology, Medical University - Varna, Bulgaria.

Background: The lack of a total numeric score of the CERAD neuropsychological battery may to some extent limit the possibilities for presenting the cognitive status and the degree of dementia.
The objective of the present study is to apply the CERAD battery in a Bulgarian population of demented and control subjects, to compute the total score for each participant, and to compare the performance of the two groups.
Methods:  a total of 164 subjects, 134 patients with dementia and 30 controls were assessed using the Bulgarian version of the CERAD battery. The total score was calculated according to the method described by Chandler et al. Mean values were compared using independent samples t-test. ROC curves were built, and the area under the curve was calculated.
Results: The total score for the whole sample has a mean value of 63.45±20.56. After correction for age and education x=79.51±20.24. The total score is significantly lower in the demented subjects compared to the control group, for both raw and corrected score. The area under the ROC curve shows values of 0.988 and 0.986 before and after correction, respectively.
Conclusion: The statistically significant difference between the results of demented and control subjects, with and without correction for age and education, support the good applicability and high informative value of the instrument. The results of ROC analysis demonstrate the high value of the battery for diagnosing dementia.

Keywords: CERAD, dementia, neuropsychological assessment, total score,

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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Dimitrov I, Aleksandrov I, Ivanov B, Kaprelyan A, Arnaoudova M. Application of the total score for the CERAD Battery in Bulgarian demented and control subjects. J of IMAB. 2017 Oct-Dec;23(4):1718-1720. DOI: 10.5272/jimab.2017234.1718

Corresponding AutorCorrespondence to: Ivan Dimitrov, MD, PhD, First Clinic of Neurology, “Sveta Marina” University Hospital; 1, Hristo Smirnenski str., 9010 Varna, Bulgaria; E-mail: indimitrov@mail.bg

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Received: 29 May 2017
Published online: 16 October 2017

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