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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2020, vol. 26, issue4
Subject Area: Medicine
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DOI: 10.5272/jimab.2020264.3368
Published online: 07 October 2020
Short Communication
J of IMAB. 2020 Oct-Dec;26(4):3368-3370
PHYSIOTHERAPY’S METHODOLOGY OF TESTING FOR PATIENTS WITH FAMILIAL AMYLOID POLYNEUROPATHY
Mariela Filipova1
, Daniela Popova1, Stanislava Bogomilova2, Gergana Nenova2, David Kantchev3,
1) Department of Kinesitherapy, Faculty of Public Health, health care and sport, SWU “Neofit Rilski" Blagoevgrad, Bulgaria.
2) Training sector, Faculty of Public health, Medical University, Varna, Bulgaria.
3) Department of Kinesitherapy, Faculty of Public health, Medical University – Sofia, Bulgaria.
ABSTRACT:
Familial amyloid polyneuropathy is a disease that occurs in southwestern Bulgaria. It causes a severe disability. The clinical picture is accompanied by weight loss, a muscle weakness, a cardiomyopathy and damage to the peripheral nervous system. The onset of symptoms is at a relatively early age (45-50 years). Specialists from Alexandrovska Hospital monitor patients with this type of disease.
Purpose: The aim of the study is to create a kinesitherapeutic algorithm for the study of patients with familial amyloid polyneuropathy.
Methods: The review study was undertaken in the Neurology department at Multidisciplinary hospital for active treatment- Blagoevgrad, Bulgaria. The study was conducted for the period 2015-2017, during which 10 patients with FAP were examined. In our algorithm we have included manual-musculе testing (ММТ) of the upper and lower limbs, an centimeter testing to measure hypotonia and a discriminant test to detect sensory disturbances.
Results: The study involved 6 women and 4 men. The average age of the studied contingent is 48.0 ± 12.7 years. In the study we found that there is a change in the study of manual muscle testing. One unit increase available. There are no statistically significant differences in the study of centimeter in the lower extremities and in the study of the senses as well. Severe muscular hypotension and distal hypoesthesia persist.
Conclusion: Unfortunately, these patients often progress rapidly. They remain disabled. Kinesitherapy, with its methods, can improve the quality of life.
Keywords: physiotherapy, familial amyloid polyneuropathy, methodology,
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Please cite this article as: Filipova M, Popova D, Bogomilova S, Nenova G, Kantchev D. Physiotherapy’s methodology of testing for patients with familial amyloid polyneuropathy. J of IMAB. 2020 Oct-Dec;26(4):3368-3370. DOI: 10.5272/jimab.2020264.3368
Correspondence to: Assoc. prof. Mariela Filipova Ph.D. Department of Kinesitherapy, SWU "N.Rilski" Blagoevgrad; 60, Ivan Mihailov str., Blagoevgrad, Bulgaria; E-mail: mariela_redm@yahoo.com
REFERENCES:
1. Adams D, Samuel D, Salma M. Treatment of familial amyloid polyneuropathy. [in French and English] La Presse Medicale. 2012 Sep; 41(9 Part 1):793-806. [Crossref]
2. Dohrn MF, Auer-Grumbach M, Baron R, Birklein F, Escolano-Lozano F, Geber C, et al. Chance or challenge, spoilt for choice? New recommendations on diagnostic and therapeutic considerations in hereditary transthyretin amyloidosis with polyneuropathy: the German/Austrian position and review of the literature. J Neurol. 2020 Jun 4. Online ahead of print. [PubMed] [Crossref]
3. Lozeron P, Mariani L-L, Dodet P, Beaudonnet G, Theaudin M, Adam C, et al. Transthyretin amyloid polyneuropathies mimicking a demyelinating polyneuropathy. J Neurology. 2018 Jul 10;91(2):e143-e152. [PubMed] [Crossref]
4. Plante-Bordeneuve V. Transthyretin familial amyloid polyneuropathy: an update. J Neurol. 2018 Apr;265(4):976-983. [PubMed] [Crossref]
5. Yamashita T, Ueda M, Misumi Y, Masuda T, Nomura T, Tasaki M, et al. Genetic and clinical characteristics of hereditary transthyretin amyloidosis in endemic and non-endemic areas: experience from a single-referral center in Japan. J Neurol. 2018 Jan;265(1):134-140. [PubMed] [Crossref]
6. Liepnieks JJ, Zhang LQ, Benson MD. Progression of transthyretin amyloid neuropathy after liver transplantation. Neurology. 2010 Jul 27;75(4):324-7. [PubMed] [Crossref].
Received: 20 August 2019
Published online: 07 October 2020