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Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2011, vol. 17, book 1
Subject Collection: Medicine
Page: 174-177
DOI: 10.5272/jimab.2011171.174
Online date: December 05, 2011
J of IMAB 2011; 17(1):174-177
UPON TYPE, FREQUENCY AND SOME CLINICAL ASPECTS OF PSYCHOTIC SYMPTOMS IN ALZHEIMER’S DISEASE
Mariana Arnaoudova
Third Psychiatric Clinic MHAT “St. Marina” - Varna;
Department of Psychiatry, MedicalUniversity, Varna, Bulgaria
ABSTRACT:
Various psychotic disorders develop often at different stages of the disease. A comprehensive approach of type, frequency and clinical aspects of the psychotic disorders patients with Alzheimer’s disease (AD) can optimize management of these conditions in patients with dementia. We examined 120 patients with probable AD. The routine clinical examination and observation were used to delineate the most common psychotic symptoms. Delusions, found in the explored patients were predominantly paranoid. The delusions are often short lived and lack complexity of that seen in schizophrenia. In number of cases they are difficult to be distinguished from confabulations. Hallucinations were mostly verbal, visual and tactile. Misidentification syndromes were identified in a considerable number of patients. They are often disputable or have been classified as delusions or hallucinations, depending on interpretation of psychotic phenomena. We discuss different forms of misidentification. The presence of psychotic symptoms predicts the occurrence and frequency of different forms of aggression and destructive behavior.
Key words: Alzheimer’s disease, psychotic symptoms, BPSD.
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REFERENCES:
1. Landes AM, Sperry SD, Strauss ME. Prevalence of Apathy, Dysphoria, and Depression in Relation to Dementia Severity in Alzheimer’s disease. J Neuropsychiatry Clin Neurosci 2005 Summer; 17(3): 342-349. doi: 10.1176/appi.neuropsych.17.3.342 CrossRef] [PubMed]
2. Alzheimer A. Uber einen eigenartigen schweren Er Krankungsprozeb der Hirnrinde. Neurologisches Centralblatt 1906; 23:1129-1136.
3. Ballard C, Saad K, Patel A, Gahir M, Solis M, Coope B, Wilcock G. The prevalence and phenomenology of psychotic symptoms in dementia sufferes. Int J Geriatr Psychiatry 1995; 10:477-85.
4. Ballard C, Walker M. Neuropsychiatric aspects of Alzheimer’s disease. Cur Psychiatry Rep 1999 Oct; 1(1):49-60. [PubMed]
5. Burns A. Misidentifications. Int Psychogeriatr 1996; 8 (Suppl3):393-397. [PubMed]
6. Burns A, Jacoby R, Levy R. Psychiatric phenomena in Alzheimer’s disease. II. Disorders of perception.. Br J Psychiatry 1990 Jul;157:76-81, 92-94. [PubMed]
7. Cadieux NL, Greve KW. Emotion processing in Alzheimer’s disease. J Int Neuropsychol Soc 19971997 Sep;3(5):411-19. [PubMed]
8. Cooper JK, Mungas D, Verma M, Weiler P. Psychotic symptoms in Alzheimer’s disease. Int J Geriatr Psychiatry 1991; 6:721-6.
9. Devanand DP, Jacobs DM, Tang M, Del Castillo-Castaneda C, Sano M. Marder K. et al. The course of psychopathologic features in mild to moderate Alzheimer’s disease. Arch Gen Psychiatry 1997 Mar;54(3):257-63. [PubMed]
10. Ellis HD, Young AW. Accounting for delusional misidentifications. Br J Psychiatr 1990 Aug; 157:239-248. [PubMed]
11. Ellis HD, Young AW, Quayle AH, de Pauw KW. Reduced autonomic responses to faces in Capgras delusion. Proceedings of the Royal Society. Proc Biol Sci. 1997 Jul 22; 264(1384:1085-1092. [PubMed]
12. Gilley DW, Wilson RS, Beckett LA, Evans DA. Psychotic symptoms and physically aggressive behavior in Alzheimer’s disease. J Am Geriatr Soc 1997 Sep; 45(9):1074-1079. [PubMed]
13. Gormley N, Rizwan M R. Prevalence and clinical correlates of psychotic symptoms in Alzheimer’s disease. Int J Geriatr Psychiatry 1998 Jun; 13(6): 410-14. DOI: 10.1002/(SICI)1099-1166(199806)13:6<410::AID-GPS787>3.0.CO;2-S CrossRef] [PubMed]
14. Holroyd S. Hallucinations and Dellusions in Dementia. Int Psychogeriatr 2000;12 /Suppl.1/: 113-117.
15. Jacoby R, Oppenheimer C, Dening T, Thomas A. Oxford Textbook of Old Age Psychiatry. Oxford University Press, 2008:428
16. Janzing JGE, Naarding P, Eling P. Depressive Symptoms Predict Slow Cognitive Decline in Mild Dementia. Dement Geriatr Cogn Disord. 2005; 20(2-3):77-81. Epub 2005 May 20. DOI: 10.1159/000085859 CrossRef] [PubMed].
17. Jeste DV, Finkel SI. Psychosis of Alzheimer’s disease and related dementia. Am J Geriatr Psychiatry 2000; 8(1):29-34. [PubMed]
18. Levy ML, Cummings JL, Fairbanks LA, Bravi D, Calvani M, Carta A. Longitudinal assessment of symptoms of depression, agitation and psychosis in 181 patients with Alzheimer’s disease. Am J Psychiatry 1996 Nov; 153(11):1438-43. [PubMed]
19. Lyketsos CG, Steinberg M, Tschanz JT, Norton MC, Steffens DC, Breitner JC. Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging. Am J Psychiatr 2000 May; 157(5):708-14. [PubMed]
20. Mega MS, Cummings JL, Fiorello T, Gornbein J. The spectrum of behavioral changes in Alzheimer’s disease. Neurology 1996; 46:130-5.
21. Mendez MF, Martin RJ, Smyth KA, WhitehousePJ. Psychiatric symptoms associated with Alzheimer’s disease. J Neuropsychiatry Clin Neurosci 1990 Winter; 2(1):28-33. [PubMed]
22. Morris RK, Rovner BW, Folstein MF, German PS. Delusions in newly admitted residents of nursing homes. Am J Psychiatry 1990; 147:299-302.
23. Roberts VJ, Ingram SM, Lamar M. Prosody impairment and associated affective and behavioral disturbances in Alzheimer’s disease. Neurology 1996; 47:1482-88.
24. Rubin EH, Drevets WC, Burke WJ. The nature of psychotic symptoms in senile dementia of the Alzheimer type. J Geriatr Psychiatry Neurol 1988 Jan;1(1):16-20. [PubMed]
25. Wragg RЕ, Jeste DV. Overview of depression and psychosis in Alzheimer’s disease. Am J Psychiatry 1989 May;146(5): 577-578. [PubMed].
Please cite this article as: Arnaoudova M. UPON TYPE, FREQUENCY AND SOME CLINICAL ASPECTS OF PSYCHOTIC SYMPTOMS IN ALZHEIMER’S DISEASE. J of IMAB 2011; 17(1):174-177. doi:10.5272/jimab.2011171.174
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