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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2015, vol. 21, issue 4
Subject Area: Medicine
Pages: 1012-1014
DOI: 10.5272/jimab.2015214.1012
Published online: 28 December 2015
J of IMAB 2015 Oct-Dec;21(4):1012-1014
IgA LINEAR BULLOUS DERMATOSIS IN CHILDHOOD.
Ivelina Yordanova 1
, Valentin Valtchev1, Dimitar Gospodinov1, Snejina Vassileva2
1) Department of Dermatology and Venereology, Faculty of Medicine, Medical University, Pleven, Bulgaria
2) Department of Dermatology and Venereology, Faculty of Medicine, Medical University, Sofia, Bulgaria.
ABSTRACT:
IgA linear bullous dermatosis, also known as chronic bullous dermatosis of childhood, is an autoimmune disease which may be idiopathic or drug-induced. The disease affects children and adults. We present a 4 years old girl with itchy polymorphic eruptions. The skin rash was presented by bullous-erosive rosette-like lesions with reddish-brown crust in the center, distributed on the skin of the face, trunk and extremities. The vesicles were filled with serous and hemorrhagic content. Laboratory examinations were within normal values according the age. Histopathological examination of the lesional skin revealed sub epidermal blister. Direct immunofluorescence of perilesional skin demonstrated linear deposition of IgA in the basement membrane. Systemic treatment with Methylprednisolon and Claritromycin was applied with satisfactory effect. The patient is under observation.
Key words: IgA linear bullous dermatosis, direct immunofluorescence, Indirect Immunofluorescence, Methylprednisolon, Claritromycin,
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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Yordanova I, Valtchev V, Gospodinov D, Vassileva S. IgA linear bullous dermatosis in childhood. J of IMAB. 2015 Oct-Dec;21(4):1012-1014. doi: http://dx.doi.org/10.5272/jimab.2015214.1012
Correspondence to: Ivelina Yordanova, PhD, MD, Assoc. Prof.; Department of Dermatology and Venereology, Faculty of Medicine, Medical University, Pleven ; 91, Gen Vladimir Vazov str. 5800 Pleven, Bulgaria; E-mail: ivelina_yordanova@abv.bg
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Received: 15 October 2015
Published online: 28 December 2015