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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2015, vol. 21, issue 4
Subject Area: Medicine
Pages: 982-986
DOI: 10.5272/jimab.2015214.982
Published online: 09 December 2015
J of IMAB 2015 Oct-Dec;21(4):982-986
PLATELET-RICH PLASMA (PRP) AND ITS APPLICATION IN THE TREATMENT OF CHRONIC AND HARD-TO-HEAL SKIN WOUNDS. A Review.
Tsvetan Sokolov 
, Boyan Valentinov, Jordan Andonov, Sevdalin Angelov, Pencho Kosev
Department of Orthopedics and Traumatology, MHAT Ruse, Ruse, Bulgaria.
ABSTRACT:
In the last few years various methods are being applied in the use of platelet-rich plasma (PRP) during treatment in different orthopedic disease. They allow improvement of local biological condition and regeneration of different types of tissues. PRP is a modern treatment strategy with worldwide recognition. There is a high concentration of platelet growth factors in small amounts of plasma. PRP and its various forms have become one of the best methods to support the healing process of various tissues. PRP is used in regenerative medicine, because it provides two of three components (growth factors and scaffolds) necessary for complete tissue regeneration. The particular reason for the appearance of lesions is important in order to select an appropriate treatment method and technical application. PRP may be used for treatment of various chronic and hard-to-heal cutaneous wounds, especially when standard conventional therapy is not good enough and surgical treatment is not possible. It reduces the duration, cost of treatment and the hospital stay. There is reduction of wound pain after starting the treatment, reduced risk of blood-borne disease transmission, wound healing is restored, and local immunity is activated.
Key words: Platelet rich plasma, platelets, platelet growth factors, chronic skin wounds,
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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Sokolov T, Valentinov B, Andonov J, Angelov S, Kosev P. Platelet-rich Plasma (PRP) and its application in the treatment of chronic and hard-to-heal skin wounds. A Review. J of IMAB. 2015 Oct-Dec;21(4):982-986. doi: http://dx.doi.org/10.5272/jimab.2015214.982
Correspondence to: Dr Tsvetan Sokolov, Department of Orthopedics and Traumatology, MHAT Ruse; 2, Nezavisimost str., 7002 Ruse, Bulgaria; E-mail: sokolovi2001@abv.bg
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Received: 17 September 2015
Published online: 09 December 2015