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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2016, vol. 22, issue 4
Subject Area: Medicine
Pages: 1352-1354
DOI: 10.5272/jimab.2016224.1352
Published online: 20 October 2016
J of IMAB 2016 Oct-Dec;22(4):1352-1354
ACUTE METHANOL INTOXICATIONS – A CHALLENGE FOR CLINICAL TOXICOLOGY
Petko Marinov1, Snezha Zlateva1, Georgi Bonchev1 
, Dobri Ivanov1, Marieta Yovcheva1, Kaloyan Georgiev3,
1) Clinic for Intensive Treatment of Acute Intoxications and Toxicoallergies, Naval Hospital – Varna, Military Medical Academy, Bulgaria
2) Department of Biology, Faculty of Pharmacy, Medical University – Varna, Bulgaria
3) Department of preclinical and clinical sciences, Faculty of Pharmacy, Medical University – Varna, Bulgaria.
ABSTRACT:
Purpose: Methanol (CH3OH) is a monohydric alcohol, vastly used both in housekeeping and industry. Although the acute methanol intoxications are rare, they may include life-threatening symptoms, substantial lethality and negative consequences such as neurological disorders and vision damage. Aim of the work is to conduct a retrospective study on the acute methanol intoxications within Varna region for a 10-year period (2006-2015).
Material/Methods: This study covers 39 patients of the Clinic for Intensive Treatment of Acute Intoxications and Toxicoallergies at Naval Hospital – Varna, all of which had their diagnosis confirmed, including gas chromatography methods.
Results: Methanol intoxication prevalence showed male/female ratio close to 2.9:1. The major part of the cases concerned economically active population, the age group of 25-60 being the most affected. In all instances an oral methanol intake has been involved. Death occurred in 14 cases (35.9%)..
Key words: methanol, acute intoxications, alcohol dehydrogenase, formaldehyde, formic acid,
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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Marinov P, Zlateva S, Bonchev G, Ivanov D, Yovcheva M, Georgiev K. ACUTE METHANOL INTOXICATIONS – A CHALLENGE FOR CLINICAL TOXICOLOGY. J of IMAB. 2016 Oct-Dec;22(4):1352-1354
DOI: 10.5272/jimab.2016224.1352.
Correspondence to: Georgi Bonchev, PhD, Head, Laboratory of Analytycal Toxicology, Military Medical Academy, Naval Hospital – Varna; 3, Chr. Smirnenski St, Varna 9010, Bulgaria; E-mail: toxilab.varna@abv.bg
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Received: 27 May 2016
Published online: 20 October 2016