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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2016, vol. 22, issue 4
Subject Area: Medicine
Pages: 1379-1382
DOI: 10.5272/jimab.2016224.1379
Published online: 12 December 2016
J of IMAB 2016 Oct-Dec;22(4):1379-1382
PLATELET-RICH PLASMA (PRP) FOR THE TREATMENT OF PROBLEMATIC SKIN WOUNDS
Tsvetan Sokolov1 
, Aneliya Manukova2, Stefka Karakoleva3, Boyan Valentinov1, Pencho Kosev1,
1) Department of Orthopedics and Traumatology, MHAT Ruse, Ruse, Bulgaria,
2) Department of Electronics, University of Ruse, Ruse, Bulgaria,
3) Department of Applied Mathematics and Statistics, University of Ruse, Ruse, Bulgaria.
ABSTRACT:
OBJECTIVE: To show platelet-rich plasma (PRP) application of problematic skin wounds and to evaluate the results from the treatment.
MATERIAL AND METHODS: A total of 31 patients with problematic skin wounds had been treated at the clinic for a period of five years (from May 2010 to September 2015) with the following patient sex ratio: male patients– 13 and female patients– 18. Average age– 46,5 (22-82). Patients with Type 2 Diabetes– 10, with decubitus ulcers– 2, traumatic– 29, with infection– 12, acute– 15, chronic– 16. Based on a scheme developed by us, all cases were treated by administering platelet-rich plasma, derived by PRGF Endoret system. Follow-up period was within 4 – 6 months (4,5 on average). We used platelet rich plasma derived by PRGF Endoret system, applied on the wound bed on a weekly basis.
RESULTS: The results have been evaluated based on the following functional scoring systems - Total wound score, Total anatomic score and Total score (20). The baseline values at the very beginning of the follow-up period were as follows: Total wound score – 10 p.; Total anatomic score – 8 p., Total score – 15 p. By the end of the treatment period the score was 0 p., which means excellent results, i.e. complete healing of the wounds.
CONCLUSION: We believe that the application of PRP may become optimal therapy in the treatment of difficult to heal wounds around joints, bone, subject tendons, plantar surface of the foot, etc., as it opens new perspectives in the field of human tissue regeneration.
Key words: problematic skin wounds, platelet rich plasma, functional scoring scales,
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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Sokolov T, Manukova A, Karakoleva S, Valentinov B, Kosev P. Platelet-rich plasma (PRP) for the treatment of problematic skin wounds. J of IMAB. 2016 Oct-Dec;22(4):1379-1382. DOI: 10.5272/jimab.2016224.1379.
Correspondence to: Dr. Tsvetan Sokolov, Department of Orthopedics and Traumatology, MHAT Ruse, Ruse, Bulgaria; 2, Nezavisimost str., 7002 Ruse, Bulgaria; E-mail: sokolovi2001@abv.bg
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Received: 14 September 2016
Published online: 12 December 2016