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Publisher: Peytchinski Publishing
ISSN: 1312-773X (Online)
Issue: 2018, vol. 24, issue2
Subject Area: Dental Medicine
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DOI: 10.5272/jimab.2018242.1978
Published online: 17 April 2018
Original article
J of IMAB. 2018 Apr-Jun;24(2):1978-1984
EFFECTS OF INDIVIDUALLY CONSTRUCTED ORAL APPLIANCE ON THE POLYSOMNOGRAPHIC PARAMETERS IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA
Lyubomir Grozev1
, Kiril Terziyski2, Aneliya Draganova2, Iliyan Hristov1,
1) Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University Plovdiv, Bulgaria.
2) Department of Pathophysiology, Faculty of Medicine, Medical University Plovdiv, Bulgaria.
ABSTRACT:
Background: Obstructive sleep apnea (OSA) is a common sleep disorder, associated with disturbed noxturnal oxygenation profile and altered sleep structure, associated with significant health problems. Oral appliances (OA) are used as an alternative therapeutic option for patients with mild to moderate OSA. Although the application of OA does not always result in a complete resolution of the sleep-disordered breathing, greater patient adherence is demonstrated. We have decided to evaluate the effect of individually constructed OA on sleep disordered breathing and sleep structure in patients with OSA.
Materials and methods: 20 patients (18 men) with OSA (age 46.3±8.1 years (mean±SD), body mass index 29.0±4.8 kg.m-2) were subjected to a full-night polysomnography (PSG), at baseline and one month after the introduction of an OA.
Results: A significant decrease in AHI (33.4±31.1 vs 45.5±30.8, p<0.001), hypopnea index (10.3±9.1 vs 18.2±11.0, p=0.023), mean duration of apneas (20.9±6.9 vs 24.1±6.4 sec, p=0.005) and average desaturation (5.6±2.4 vs 8.5±3.0 %, p<0.001), after therapy and at baseline, respectively, was registered. Sleep structure was improved as indicated by an increase in REM (16.1±6.2vs 12.3±8.2 % of total sleep time, p=0.016) and a decrease in arousal index (31.0±14.2 vs 46.4±12.0, p<0.001).
Conclusion: OA is a reasonable alternative for the treatment of patients with moderate and severe OSA, resulting in an improvement of the polysomnographic parameters and expressed by excellent patient compliance.
Keywords: oral appliance, obstructive sleep apnea, polysomnography,
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Please cite this article as: Grozev L, Terziyski K, Draganova A, Hristov I. Effects of individually constructed oral appliance on the polysomnographic parameters in patients with obstructive sleep apnea. J of IMAB. 2018 Apr-Jun;24(2):1978-1984. DOI: 10.5272/jimab.2018242.1978
Correspondence to: Lyubomir Grozev, Department of Prosthetic Dentistry, Faculty of Dental Medicine, Medical University Plovdiv; 15A, Vassil Aprilov Blvd., Plovdiv, Bulgaria; E-mail: doktorgrozev@gmail.com,
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Received: 15 January 2018
Published online: 17 April 2018