head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing
ISSN: 1312-773X (Online)
Issue: 2018, vol. 24, issue2
Subject Area: Medicine
DOI: 10.5272/jimab.2018242.2069
Published online: 21 June 2018

Original article

J of IMAB. 2018 Apr-Jun;24(2):2069-2073
Veselinka Nestorova1ORCID logo Corresponding Autoremail, Borislav Ivanov2ORCID logo, Iskra Mircheva3ORCID logo, Ivan Dimitrov4ORCID logo, Ara Kaprelyan5ORCID logo, Kalina Drenska5ORCID logo,
1) Department of Physiotherapy, rehabilitation, thalassotherapy, occupational diseases, Faculty of Public Health, Medical University, Varna, Bulgaria.
2) Department of clinical medical sciences, Faculty of Dental Medicine, Medical University, Varna, Bulgaria.
3) Department of social medicine and healthcare organization, Faculty of Public Health, Medical University, Varna, Bulgaria.
4) Department of nursing, Sliven affiliate, Medical University, Varna, Bulgaria.
5) Department of Neurology and neuroscience, Faculty of Medicine, Medical University, Varna, Bulgaria.

Chronic neurotoxicity of lead is a major problem in all countries around the world. Long-term exposure to lead in the environment has recently become of interest as a possible risk factor for cognitive impairment in workers exposed to lead. The consequences for the brain after cessation of the exposure are also subject to research.
The aims of our study were: to investigate and analyze cognitive impairment in workers in professional contact with lead.
For the purpose of the study, a total of 72 workers in chronic professional contact with lead aerosols were examined. The investigated men (n = 72) were aged 39.4 ± 10.4 (19 - 58) years with an average duration of service of 13.0 ± 8.7 (1 - 33) years and mean lead concentration in blood of 43.4 ± 9.0 μg / dl. The screening set included a subjective cognitive impairment survey, a depression scale, a set of cognitive tests (MMSE, IST, DRT, CDT), and a scale for activities of daily living (4-IADL Score).
With the increase of lead levels in the blood a statistically reliable trend is observed for decrease of MMSE, IST and CDT scores. Eleven of the screened individuals (15.28%) achieved a score of <7 which determines them as positively screened according to DRT. Possible mild cognitive impairment manifesting with disturbance of construction praxis, planning, short-term memory and concentration could probably be attributed to the toxic effects of lead and has a potential to be a subclinical marker.

Keywords: lead in blood, cognitive disorders, professional exposure to lead,

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Please cite this article as: Nestorova V, Ivanov B, Mircheva I, Dimitrov I, Kaprelyan A, Drenska K. Occupational Lead Exposure and Cognition in Adults. J of IMAB. 2018 Apr-Jun;24(2):2069-2073. DOI: 10.5272/jimab.2018242.2069

Corresponding AutorCorrespondence to: Veselinka Nestorova, Department of Physiotherapy, rehabilitation, thalassotherapy, occupational diseases, Medical University, Varna; 55, Marin Drinov str., 9002 Varna, Bulgaria; E-mail: dr_nestorova@yahoo.de,

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Received: 08 May 2018
Published online: 21 June 2018

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