head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing
ISSN: 1312-773X (Online)
Issue: 2018, vol. 24, issue2
Subject Area: Medicine
DOI: 10.5272/jimab.2018242.2074
Published online: 21 June 2018

Case reports

J of IMAB. 2018 Apr-Jun;24(2):2074-2076
Veselinka Nestorova1ORCID logo Corresponding Autoremail, Borislav Ivanov2ORCID logo, Ivan Dimitrov3ORCID logo, Kalina Drenska4ORCID logo, Ara Kaprelyan4ORCID logo,
1) Department of Physiotherapy, rehabilitation, thalassotherapy, occupational diseases, Faculty of Public Health, Medical University, Varna, Bulgaria.
2) Department of clinical medical sciences, Faculty of Dental Medicine, Medical University, Varna, Bulgaria.
3) Department of nursing, Sliven affiliate, Medical University, Varna, Bulgaria.
4) Department of Neurology and neuroscience, Faculty of Medicine, Medical University, Varna, Bulgaria.

Amyotrophic lateral sclerosis (ALS) is a severe and fatal neurodegenerative disorder affecting both the upper and lower motor neurons. We present the clinical cases of four patients with ALS and vibration syndrome. All patients had over 20 years of exposure to general and local vibrations and common subjective complaints: pain, paresthesia, twitching and weakness of limb muscles. Evidence of ALS syndrome was demonstrated by the abnormal neurological examination (pseudobulbar syndrome and pyramidal signs) as well as by neurophysiological studies (peripheral motor neuron degeneration). We discuss the possible relationship between the exposure to general and local vibrations and the ALS syndrome in our patients, and the role of vibrations as a possible risk factor for the disease. Occupational contact with chemicals and pesticides is also discussed as a risk factor.

Keywords: amyotrophic lateral sclerosis, general and local vibrations, chemicals, pesticides,

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Please cite this article as: Nestorova V, Ivanov B, Dimitrov I, Drenska K, Kaprelyan A. Amyotrophic Lateral Sclerosis and Effects of Vibrations. J of IMAB. 2018 Apr-Jun;24(2):2074-2076. DOI: 10.5272/jimab.2018242.2074

Corresponding AutorCorrespondence to: Veselinka Nestorova, Department of Physiotherapy, rehabilitation, thalassotherapy, occupational diseases, Medical University, Varna; 55, Marin Drinov str., 9002 Varna, Bulgaria; E-mail: dr_nestorova@yahoo.de,

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Received: 08 May 2018
Published online: 21 June 2018

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