head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2020, vol. 26, issue1
Subject Area: Medicine
-
DOI: 10.5272/jimab.2020261.2966
Published online: 02 March 2020

Original article

J of IMAB. 2020 Jan-Mar;26(1):2966-2969
ALLERGIC CONTACT DERMATITIS IN BULGARIA – COMPARISSON BETWEEN 1987 AND 2017
Yoanna Velevska-Vatova1ORCID logo Corresponding Autoremail, Razvigor Darlenski2ORCID logo, Тsveta Kalinova1ORCID logo, Rumyana Yankova3ORCID logo, Sonya Marina1ORCID logo, Jana Kazandjieva4ORCID logo,
1) Department of Infection diseases, Parasitology and Dermatovenerology, Medical University, Varna,
2) Clinic of Dermatology, Adcibadem Cityclinic Tokuda Hospital, Sofia,
3) Pulmed Hospital Plovdiv,
4) Department of Dermatology and Venerology, Medical University, Sofia, Bulgaria.

ABSTRACT:
In our study, we are trying to show how the data on allergic contact dermatitis has changed over the years in Bulgaria.
Purpose: The socio-economic changes had an impact on the medical data since the fall of the Berlin Wall. We investigated how this changes reflected especially on contact allergy.
Material/Methods: In order to achieve our goal, we compared the Bulgarian results from epicutaneous testing in 1987 and 2017.
Results: Allergens to which the greatest number of patients were sensitized in 1987 in the cities of Sofia and Plovdiv were Potassium dichromate, 4-isopropylamino diphenylamine, Formaldehyde, Nickel (II) sulfate, and Parephenylenediamine (PPD). In 2017 - for the same number of patients and in the same cities, top 5 allergens were Nickel (II)sulfate hexahydrate, Cobalt(II)chloride hexahydrate, Colophonium, Potassium dichromate, Myroxylon pereirae resin.
Conclusions: The most alarming are the data on how much sensitization to nickel increased in 2017 due to the continuous use of this metal. The positive reactions to potassium dichromate were more in 1987, whereas in 2017 due to the concentration adjustment for hexavalent chromium in cement, the number of cases with contact allergy to potassium dichromate was reduced.
These data show that until we succeed in regulation and prevention, we cannot hope to seriously reduce contact allergy cases.

Keywords: Frequency, contact dermatitis, prevalence,

pdf - Download FULL TEXT /PDF 670 KB/
Please cite this article as: Velevska-Vatova Y, Darlenski R, Kalinova Ts, Yankova R, Marina S, Kazandjieva J. Allergic contact dermatitis in Bulgaria – comparisson between 1987 and 2017. J of IMAB. 2020 Jan-Mar;26(1):2966-2969. DOI: 10.5272/jimab.2020261.2966

Corresponding AutorCorrespondence to: Yoanna Velevska-Vatova, Department of Infection diseases, Parasitology and Dermatovenerology, Medical University, Varna; Pop Hariton str. 8, fl 3, Varna, Bulgaria; E-mail: ioanna.velevska@abv.bg

REFERENCES:
1. Kazandjieva J, Darlenski R, Yankova R, Berova N, Tonev S, Gospodinov D, et al. National consensus for the diagnosis and treatment of contact dermatitis. Dermatol and Venereol. 2011; 24(2):3-16. [in Bulgarian]
2. Martin SF. Allergic contact dermatitis: xenoinflammation of the skin. Curr Opin Immunol. 2012 Dec;24(6):720-29.  [PubMed] [Crossref]
3. Berova N, Kazandjieva J. Epicutaneous testing history. Dermatol and Venereol. 2018; 1:41-43. [in Bulgarian]
4. Trifunova B, Kazandjieva J, Demerdjieva Z. Allergic contact dermatitis in childhood - features in etiopathogenesis, clinic, diagnosis and therapy. Dermatol and Venereol. 2018; 57(2):3-10. [in Bulgarian]
5. Alinaghi F, Bennike NH, Egeberg A, Thyssen JP, Johansen JD. Prevalence of contact allergy in the general population: A systematic review and meta-analysis. Contact Dermatitis. 2019 Feb;80(2):77-85. [PubMed] [Crossref]
6. Nielsen NH, Menne T. Allergic contact sensitization in an unselected Danish population. The Glostrup Allergy Study, Denmark. Acta Derm Venereol. 1992 Nov;72(6):456-60. [PubMed]
7. Stransky L, Jankova R, Krasteva M. Comparative studies on the changes in the structure of the causative agents of  contact dermatitis and eczema in the cities of Sofia and Plovdiv. Dermatol and venereol. 1989; 28(2):9-13. [in Bulgarian]
8. Darlenski R, Kazandjieva J, Pramatarov K. The many faces of nickel allergy. Int J Dermatol.2012 May;51(5):523-30. [PubMed] [Crossref]
9. Kazandjieva J, Darlenski R. New faces of contact dermatitis. Allergol and dermatol. 2011; 1:11-14. [in Bulgarian]
10. Darlenski R, Demerdjieva Z, Kazandjieva J, Tsankov N. Systemic contact dermatitis to Nickel. OA Dermatol. 2014 Apr 11;2(1):7.
11. Kazandjieva J, Kircheva К, Nikolova A, Tsankov N. Allergic contact dermatitis from paraphenylenediamine. Modern Medicine. 2008; 59(1):44-46. [in Bulgarian]
12. Gergovska M, Darlenski R, Kazandjieva J. Contact dermatitis from Parafenylenediamine. Medinfo. 2013; XIII(5):8-9. [in Bulgarian]
13. Darlenski R, Kazandjieva J, Tsankov N. Hair Extensions: Novel “Source” of a Well- Known Contact Allergen. SKINmed. 2013; 11:51-53.

Received: 12 September 2019
Published online: 02 March 2020

back to Online Journal