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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2020, vol. 26, issue2
Subject Area: Dental Medicine
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DOI: 10.5272/jimab.2020262.3187
Published online: 11 June 2020
Case report
J of IMAB. 2020 Apr-Jun;26(2):3187-3193
PRIMARY EXTRANODAL NON-HODGKIN’S LYMPHOMA INVOLVING RIGHT MAXILLA
Elitsa Deliverska1
, Evgenii Hadjiev2, Lutchezar Stefanov1, Gergana Tsvetkova2, Emel Bekirova2, Sadeta Parusheva1,
1) Department of Dental, Oral and Maxillofacial surgery, Faculty of Dental Medicine, Medical University - Sofia.
2) Clinic of Clinical Hematology, UMHAT “Alexandrovska” - Sofia, Bulgaria.
ABSTRACT:
Background: Lymphoma in a single bone without any nodal or visceral involvement is known as primary intra-osseous lymphoma, which is a very uncommon malignancy. It constitutes 3.1% of malignant bone tumours and 5% of extranodal lymphomas, and the incidence is only 0.6% in the jaws. These tumours can be primary or secondary (in the disseminated forms). The primary intra-osseous lymphoma of the jaws is a challenge to diagnose, because of their various clinical presentation, which can mimic an odontogenic tumour, cyst or a fibro-osseous lesion.
Purpose: This case report discusses a rare malignancy of jaw bones, including clinical presentation, histopathologic features, immunologic profile, PET scan, management and prognosis.
Material and methods: We present a case of a primary intraosseous lymphoma in a 45-year-old female who presented with a swelling in the right maxilla. It highlights the importance of recognizing rare entities that may present in the jaws, the impact of the disease and its management.
Results: Jaw localization of Non-Hodgkin’s lymphoma is rare. Clinical symptomatology and radiological signs are poorly contributive. The diagnosis relies on the histopathological analysis.
Conclusion: One of the diagnostic problems with regard to NHL is the variable nature of clinical symptoms. A biopsy allowed diagnosing an intra-oral bone lymphoma, and the patient was referred to the hematooncology unit for treatment.
Keywords: non Hodgkin’s lymphoma, extranodal, jaws,
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Please cite this article as: Deliverska E, Hadjiev E, Stefanov L, Tsvetkova G, Bekirova E, Parusheva S. Primary Extranodal Non-Hodgkin’s Lymphoma Involving Right Maxilla. J of IMAB. 2020 Apr-Jun;26(2):3187-3193. DOI: 10.5272/jimab.2020262.3187
Correspondence to: Elitsa Georgieva Deliverska, Department of Dental, Oral and Maxillofacial surgery, Faculty of Dental Medicine, Medical University- Sofia; 1, Georgi Sofiiski Blvd., Sofia 1431, Bulgaria; E-mail: elitsadeliverska@yahoo.com
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Received: 01 July 2019
Published online: 11 June 2020