head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2021, vol. 27, issue1
Subject Area: Medicine
DOI: 10.5272/jimab.2021271.3564
Published online: 28 January 2021

Case report

J of IMAB. 2021 Jan-Mar;27(1):3564-3567
Gergana Tosheva1ORCID logo Corresponding Autoremail, Mira Siderova1ORCID logo, Elitsa Encheva2ORCID logo, Doroteya Malinova3ORCID logo,
1) Endocrinology Department, Faculty of Medicine, Clinic of Endocrinology and Metabolic Diseases, University Hospital St. Marina, Medical University - Varna, Bulgaria.
2) Radiotherapy Department, Faculty of Medicine, Clinic of Diagnostics Imaging and Radiotherapy, University Hospital St. Marina, Medical University - Varna, Bulgaria.
3) Department of General and Clinical Pathology, Faculty of Medicine, Clinic of General and Clinical Pathology, Forensic Medicine and Deontology, University Hospital St. Marina, Medical University - Varna, Bulgaria.

Introduction: We present a patient with carcinoma of the tongue with а lymph node and thyroid metastasеs. The squamous cell cancer of the tongue’s 5-year survival rate has not been improved in the last three decades. Most common sites of metastases are the locoregional lymph nodes, followed by distant pulmonary, liver, bone and skin metastasеs. Only ten cases of metastases to the thyroid gland are reported in the literature. 
Case report: A 79-year old man presented to the University Hospital in Varna, Bulgaria. Two months before admission, he noticed swelling of the tongue and progressive weight loss. The inspection of the oral cavity revealed a lesion on the left margin of the tongue. A biopsy was performed with a histological result of differentiated squamous cell carcinoma of the tongue. A computed tomography scan of the head and neck region discovered a lesion in the right thyroid lobe. 18-fluoro-2-deoxy-glucose-positron emission tomography imaging showed a metabolically active tumor of the tongue with hypermetabolic metastatic cervical lymph nodes and a zone with abnormally elevated fixation of 18F-FDG in the central part of the soft palate. The described thyroid nodule did not have an increased tracer uptake. It was cytologically assessed after fine-needle aspiration biopsy (FNAB) as a metastasis from squamous cell carcinoma of the tongue.
Conclusions: Distant metastases from tongue cancer to the thyroid gland are extremely rare and mostly occur in the advanced stages of malignancy.

Keywords: tongue, matastasis, thyroid gland,

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Please cite this article as: Tosheva G, Siderova M, Encheva E, Malinova D. Thyroid metastasis of a squamous cell carcinoma of the tongue - a rare case report. J of IMAB. 2021 Jan-Mar;27(1):3564-3567. DOI: 10.5272/jimab.2021271.3564

Corresponding AutorCorrespondence to: Gergana Tosheva Marinova, MD, Clinic of Endocrinology, University Hospital “St. Marina” Varna; 1, Hr. Smirnenski Blvd., 9010 Varna, Bulgaria; E-mail: gergana_tosheva@abv.bg

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Received: 02 January 2020
Published online: 28 January 2021

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