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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2021, vol. 27, issue3
Subject Area: Medicine
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DOI: 10.5272/jimab.2021273.3829
Published online: 01 July 2021
Original article
J of IMAB. 2021 Jul-Sep;27(3):3829-3834
UNILATERAL PROFOUND DEAFNESS – A POSSIBLE MECHANISM
Konstantin Georgiev1
, Yana Pacholova2,
1) LOR Department; MBAT Varna; Military Medical Academy, Bulgaria.
2) Family Centre Pan, Psychological and Speech Therapy Practice, Varna, Bulgaria.
ABSTRACT:
Purpose: To explain the clinical findings of patients with profound unilateral deafness who have recovered the hearing function after a combined treatment of hyperbaric oxygenation and dehydrant therapy.
Material and method: 11 patients with profound sudden unilateral hearing loss above 90 dB SPL, intolerance to sounds similar to recruitment, at levels 10-20 dB above the hearing threshold (105-120 dB SPL), positive glycerol test and unexpected good recovery of hearing within 1-2 months are described.
Results: All patients have perfect outcome results without the use of glucocorticoids.
Conclusions: Based on articles about experiments with genetically modified animals and acquired deafness, we propose a possible mechanism of damage explaining the clinical findings and the favorable outcome of the disease – a disconnection between the tectorial membrane and stereocilia. Thus mechano-electrical transducer (MET) of hair cells cannot be activated. The combined use of hyperbaric oxygenation and dehydrant medications can lead to recovery of the hearing function.
Keywords: Unilateral Sensorineural Hearing Loss, Tectorial Membrane, Hair Cells,
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Please cite this article as: Georgiev K, Pacholova Y. Unilateral profound deafness – a possible mechanism. J of IMAB. 2021 Jul-Sep;27(3):3829-3834. DOI: 10.5272/jimab.2021273.3829
Correspondence to: Konstantin Georgiev, LOR Department, Multiprofile Base for Active Treatment - Varna, Military Medical Academy; 3, Hristo Smirnenski Str., 9000 Varna, Bulgaria; E-mail: drkgeorgiev@abv.bg
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Received: 17 October 2020
Published online: 01 July 2021