head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2022, vol. 28, issue4
Subject Area: Medicine
DOI: 10.5272/jimab.2022284.4749
Published online: 19 December 2022

Case report
J of IMAB. 2022 Oct-Dec;28(4):4749-4752
Radka Komitova1, 2ORCID logo Corresponding Autoremail, Georgi Kiprin3ORCID logo, Elica Golgocheva-Markova4ORCID logo,
1) Department of Infectious Diseases, Parasitology and Tropical Medicine, Faculty of Medicine, Medical University of Plovdiv, Bulgaria.
2) Department of Infectious Diseases, University Hospital St. George, Plovdiv, Bulgaria.
3) Department of Gastroenterology, University Hospital Eurohospital, Plovdiv, Bulgaria.
4) National Reference Laboratory "Hepatitis viruses", National Center of Infectious and Parasitic Diseases, Sofia, Bulgaria.

Chronic hepatitis C is a global health threat. Most individuals infected with the hepatitis C virus (HCV) will inevitably progress to chronic infection, leading to cirrhosis and hepatocellular carcinoma. The current use of direct-acting antiviral (DAA) agents has changed the outlook for the treatment resulting in a cure for a short time. Recently acquired hepatitis C, also known as acute hepatitis, should be treated with regimens similar to chronic hepatitis C. We report a case of recently acquired hepatitis C manifested with jaundice, confirmed by a positive HCV RNA result and seroconversion. The patient was referred to a gastroenterologist with his girlfriend with newly diagnosed chronic hepatitis C for further evaluation and treatment. Both underwent DAA treatment with glecaprevir/pibrentasvir for two months. Upon completion of the therapy and 12 weeks later, HCV PCR was undetected in both cases. We treated our patient long before the onset of chronic liver disease and long-term complications. The current case underscores the importance of asking about potential ongoing exposure to an HCV-infected person.

Keywords: Direct-acting antiviral therapy, exposure to an HCV-infected person, early HCV infection, sustained virological response,

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Please cite this article as: Komitova R, Kiprin G, Golgocheva-Markova E. A cure for recently acquired hepatitis C. J of IMAB. 2022 Oct-Dec;28(4):4749-4752. DOI: 10.5272/jimab.2022284.4749

Corresponding AutorCorrespondence to: Prof. Radka Komitova, MD, PhD, Department of Infectious Diseases, Medical University, Plovdiv; 15A, Vassil Aprilov Blvd., 4000 Plovdiv, Bulgaria; E-mail: Radka.komitova@yahoo.com

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Received: 03 May 2022
Published online: 19 December 2022

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