 |
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2023, vol. 29, issue3
Subject Area: Dental Medicine
-
DOI: 10.5272/jimab.2023293.5052
Published online: 22 August 2023
Case report
J of IMAB. 2023 Jul-Sep;29(3):5052-5056
AMELOBLASTOMA OF THE JAW BONES: CLINICAL STUDY AND CASE REPORT
Simeon Dimanov1
, Yanko Yankov2, 3, Lyuben Stoev4, 5,
1) Department of Oral Surgery, Faculty of Dental Medicine, Medical University - Varna, Bulgaria.
2) Clinic of Maxillofacial Surgery, UMHAT "Sveta Marina", Medical University - Varna, Bulgaria.
3) Department of General and Operative Surgery, Faculty of Medicine, Medical University - Varna, Bulgaria.
4) Clinic of General and Clinical Pathology, UMHAT "Sveta Marina", Medical University - Varna, Bulgaria.
5) Department of General and Clinical Pathology, Forensic Medicine and Deontology, Faculty of Medicine, Medical University - Varna, Bulgaria.
ABSTRACT:
Ameloblastoma's origin is the epithelium of ectodermal origin, which means they are tumors arising from the cells around the tooth root or, in close approximation, derived from the ectoderm. It is a benign but locally aggressive tumor with a high tendency to recur. Patients after ameloblastoma treatment need a life-long follow-up.
We present an 82-year-old female patient diagnosed with ameloblastoma and treated by us. She has been referred to the clinic by doctor of dental medicine because of a routine panoramic rentgenography, which displayed rentgenographic evidence for a cyst-like tumor formation on her mandible. The patient did not have any complaints.
The patient was reffered for further paraclinical imaging tests – dental panoramic radiography (OPG) and cone beam computed tomography (CBCT). The location and borders of the lesion were determined - it was circumferentially attached to the root of 44 tooth, well-outlined linea albuginea was present, the diameter of the lesion was approximately 26 mm.
Bone curettage was the treatment plan - the surgical intervention in this volume was chosen as a consequence of the refusal of the patient of a partial mandibulectomy and according to her age – 82.
The histopathological examination of the curettage revealed a locally infiltrative tumor process engaging the submitted bone and fibrous tissue. The final pathological diagnosis was conventional ameloblastoma with a predominantcanthomatous pattern.
On the control panoramic rentgenography one year after the operation, no pathological changes in the field of the operative site were found.
Keywords: benign odontogenic tumor, jaw tumor, maxillofacial surgery, oral surgery, pathology,
- Download FULL TEXT /PDF 1554 KB/
Please cite this article as: Dimanov S, Yankov Y, Stoev L. Ameloblastoma of the jaw bones: clinical study and case report. J of IMAB. 2023 Jul-Sep;29(3):5052-5056.
[Crossref - 10.5272/jimab.2023293.5052]
Correspondence to: Simeon Dimanov, DMD, Department of Oral Surgery, Faculty of Dental Medicine, Medical University – Varna; 84, Tsar Osvoboditel Blvd. floor 6, office 615, Varna, Bulgaria;
E-mail: drdimanov@yahoo.com
REFERENCES:
1. Masthan KM, Anitha N, Krupaa J, Manikkam S. Ameloblastoma. J Pharm Bioallied Sci. 2015 Apr;7(Suppl 1):S167-70. [ PubMed ]
2. Palanisamy JC, Jenzer AC. Ameloblastoma. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2023 Jan 20. [PubMed]
3. Daley TD, Wysocki GP, Pringle GA. Relative incidence of odontogenic tumors and oral and jaw cysts in a Canadian population. Oral Surg Oral Med Oral Pathol. 1994 Mar;77(3):276-80. [PubMed]
4. Ghai S. Ameloblastoma: An Updated Narrative Review of an Enigmatic Tumor. Cureus. 2022 Aug 6;14(8):e27734. [PubMed]
5. Becelli R, Carboni A, Cerulli G, Perugini M, Iannetti G. Mandibular ameloblastoma: analysis of surgical treatment carried out in 60 patients between 1977 and 1998. J Craniofac Surg. 2002 May;13(3):395-400; discussion 400. [PubMed]
6. Gamoh S, Akiyama H, Tominaga K, Nakajima M, Kakudo K, Tanaka A, et al. Simultaneous occurrence of keratocystic odontogenic tumor and ameloblastoma in the mandible: A case report. Oncol Lett. 2015 Aug;10(2):785-789. [PubMed]
7. Gupta RK, Dugal AG, Pawar SR, Khandelwal SG, Iyengar A. A Rare Simultaneous Occurrence of Odontogenic Keratocyst and Unicystic Ameloblastoma in Mandible: A Case Report. J Clin Diagn Res. 2016 Aug;10(8):ZD01-4. [PubMed]
8. Slootweg PJ, Müller H. Malignant ameloblastoma or ameloblastic carcinoma. Oral Surg Oral Med Oral Pathol. 1984 Feb;57(2):168-76. [PubMed]
9. Ameloblastoma. Cleveland Clinic. 11/30/2021. [Internet]
10. Mahmoud SAM, Amer HW, Mohamed SI. Primary ameloblastic carcinoma: literature review with case series. Pol J Pathol. 2018;69(3):243-253. [PubMed]
11. Larsson A, Almerén H. Ameloblastoma of the jaws. An analysis of a consecutive series of all cases reported to the Swedish Cancer Registry during 1958-1971. Acta Pathol Microbiol Scand A. 1978 Sep;86A(5):337-49. [PubMed]
12. Shear M, Singh S. Age-standardized incidence rates of ameloblastoma and dentigerous cyst on the Witwatersrand, South Africa. Community Dent Oral Epidemiol. 1978 Jul;6(4):195-9. [PubMed]
13. Kramer IRH, Pindborg JJ, Shear M. Definitions and Explanatory Notes. In: Histological Typing of Odontogenic Tumours. 2nd ed. WHO. Springer, Berlin, Heidelberg. 1992. Chapter 3. 11-14 p. [Crossref]
14. Cadavid AMH, Araujo JP, Coutinho-Camillo CM, Bologna S, Lemos CA, Jr., Lourenço SV. Ameloblastomas: current aspects of the new WHO classification in an analysis of 136 cases. Surg Exp Pathol. 2019; 2:17. [Crossref]
15. Wright JM, Vered M. Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Odontogenic and Maxillofacial Bone Tumors. Head Neck Pathol. 2017 Mar;11(1):68-77. [PubMed]
16. Sham E, Leong J, Maher R, Schenberg M, Leung M, Mansour AK. Mandibular ameloblastoma: clinical experience and literature review. ANZ J Surg. 2009 Oct;79(10):739-44. [PubMed]
17. Faras F, Abo-Alhassan F, Israël Y, Hersant B, Meningaud JP. Multi-recurrent invasive ameloblastoma: A surgical challenge. Int J Surg Case Rep. 2017; 30:43-45. [PubMed]
18. Sozzi D, Cassoni A, De Ponti E, Moretti M, Pucci R, Spadoni D, et al. Effectiveness of Resective Surgery in Complex Ameloblastoma of the Jaws: A Retrospective Multicenter Observational Study. Cancers (Basel). 2022 Sep 22;14(19):4608. [PubMed]
Received: 20 February 2023
Published online: 22 August 2023