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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2024, vol. 30, issue2
Subject Area: Medicine
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DOI: 10.5272/jimab.2024302.5490
Published online: 29 April 2024
Original article
J of IMAB. 2024 Apr-Jun;30(2):5490-5494
CARRIERSHIP OF ANTI-TOXOCARA IGG ANTIBODIES AMONG PATIENTS WITH CLINICAL ALLERGY
Lyudmil Stoyanov
, Ivelin Angelov,
Department of Infectious diseases, epidemiology, parasitology and tropical medicine, Medical University – Pleven, Bulgaria.
ABSTRACT:
Introduction: Toxocariasis is a zoonotic helminthosis caused by nematodes of the Toxocara genus. Humans are accidental hosts for the parasite. As Toxocara larvae migrate throughout the organism, they lead to the formation of allergic reactions.
Purpose: Our goal is to study the connection between clinical allergy and toxocariasis by examining the frequency of infection with Toxocara spp. and the levels of anti-Toxocara IgG antibodies in patients with acute urticaria, chronic urticaria and other forms of allergic reactions.
Materials and methods: Between 2018 and 2023, we tested 310 allergic patients serologically for anti-Toxocara IgG antibodies via the ELISA method. In addition we also tested 47 non-allergic people as a control group.
Results: In our study, we detected anti-Toxocara IgG antibodies in 25,48% of allergic patients. We found that patients with allergy were statistically more likely to be seropositive for anti-Toxocara antibodies compared to the control group. We did not find any significant difference in the levels of antibodies between different types of allergic reactions.
Conclusion: Our results show the need for serological testing for toxocariasis in all allergic patients. Additional methods and/or diagnostic markers are needed for proper assessment of cases and whether treatment is necessary.
Keywords: Тoxocara, Toxocariasis, allergy, urticaria, ELISA,
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Please cite this article as: Stoyanov L, Angelov I. Carriership of anti-Toxocara IgG antibodies among patients with clinical allergy. J of IMAB. 2024 Apr-Jun;30(2):5490-5494. [Crossref - 10.5272/jimab.2024302.5490]
Correspondence to: Dr. Lyudmil Stefanov Stoyanov, Department of Infectious diseases, epidemiology, parasitology and tropical medicine, Medical University – Pleven; 1, St. Kliment Ohridski Str., 5800 Pleven, Bulgaria; E-mail: ludmilstoyanov92@abv.bg
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Received: 19 January 2024
Published online: 29 April 2024