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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2024, vol. 30, issue4
Subject Area: Medicine
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DOI: 10.5272/jimab.2024304.5819
Published online: 17 October 2024
Original article
J of IMAB. 2024 Oct-Dec;30(4):5819-5823
ASSOCIATION OF HELICOBACTER PYLORI INFECTION AND GASTROINTESTINAL DISEASE IN CHILDREN
Vanya Nedkova-Milanova1
, Zornitsa Gorcheva2, Ivaylo Pakov3, Milena Karcheva3,
1) Department of General Medicine, Faculty of Public Health, Medical University-Pleven, Bulgaria.
2) Department of Therapeutic Care, Faculty of Health Care, Medical University-Pleven, Bulgaria.
3) Department of Infectious Diseases, Epidemiology, Parasitology and Tropical Medicine, Faculty of Public Health, Medical University-Pleven, Bulgaria.
ABSTRACT:
Purpose: The purpose of this study was to assess the association between some clinical and epidemiological factors and the prevalence of Helicobacter Pylori (H. pylori) infection in children visited a paediatrics ambulatory care at University Hospital - Pleven for various symptoms pointing to gastritis and peptic ulcer.
Materials and methods: an epidemiological study was conducted for the period June-September 2023. In total, 133 children aged from 2 to 18 years were evaluated. All visited a paediatrics ambulatory care at University Hospital - Pleven for various complaints pointing to gastritis and peptic ulcer.
Results: During the study period, we recruited a total of 133 children and adolescents (age range 2-18 years, mean age 9.36 ± 4.08 years). More patients were males (54.14%) than females (45.86%). The most frequent symptoms were abdominal pain (51.88%), nausea and vomiting (21.80%), and losing weight (10.53%). The social status of the families is good - parents with a university education predominate (49.62%). There are risk factors for the presence of infection and the development of gastritis and ulcers in children: family history of H. pylori infection (47.37%) and use of unsuitable foods (48.87%). A high positivity is found for H. pylori (40.43%).
Conclusions: Early diagnosis and etiological treatment of H. pylori infection reduces the risk of developing gastric complications like chronic gastritis, ulcer diseases and gastric cancer.
Keywords: H. pylori, children, gastritis, peptic ulcer,
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Please cite this article as: Nedkova-Milanova V, Gorcheva Z, Pakov I, Karcheva M. Association of Helicobacter Pylori infection and gastrointestinal disease in children. J of IMAB. 2024 Oct-Dec;30(4):5819-5823. [Crossref - 10.5272/jimab.2024304.5819]
Correspondence to: Vanya Nedkova-Milanova, MD, PhD, Department of General Medicine, Medical University-Pleven; 1, Sv. Kliment Ohridski Str., 5800 Pleven, Bulgaria; E-mail: vania_milanova@yahoo.com
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Received: 31 August 2024
Published online: 17 October 2024