Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN:
1312-773X (Online)
Issue:
2025, vol. 31, issue3
Subject Area:
Medicine
-
DOI:
10.5272/jimab.2025313.6428
Published online: 02 September 2025
Original article
J of IMAB. 2025 Jul-Sep;31(3):6428-6432
ANEMIA IN PREGNANCY, STUDY IN BITOLA, NORTH MACEDONIA
Biljana Ilkovska1


, Bisera Kotevska-Trifunova2
, Filip Ilkovski3
,
1) University St. Kliment Ohridski Bitola, Higher Medical School Bitola, Department of laboratory diagnostics, PHO Clinical hospital dr. Trifun Panovski Bitola, R. Macedonia.
2) Department of Dermatology and Venereology, Acibaden city clinic, Tokuda hospital - Sofia, Bulgaria.
3) High Medical School Dr. Trifun Panovski Bitola, R. Macedonia.
ABSTRACT:
Purpose: Anemia in pregnancy is a national problem because it reflects the value of people's socioeconomic well-being, and its influence is very large on the quality of human resources. Anemia during pregnancy has been a significant health problem worldwide for many years. Our study was designed to assess the prevalence of anemia at the time of diagnosis of pregnancy during the third trimester in the city hospital of Bitola.
Material/Methods: This pilot study was performed in a Clinical hospital in Bitola (R. Macedonia). The total number of participants was 173 pregnant women. Complete blood count (CBC) - CBC was determined in ethylenediaminetetraacetic acid (K-EDTA) blood samples -using Sysmex XN 550 (Sysmex Co, Kobe, Japan).
Conclusions: Anemia in pregnancy is a mild public health problem in Bitola. The diet of pregnant women, which does not reflect a varied and balanced diet, causes an iron deficiency. The main risk factors were age of the pregnant woman. Further, we recommend ongoing education about effects of anemia, especially among women with low education and the population of adolescent women and women of reproductive age in general.
Keywords: anemia, pregnancy, iron deficiency anemia,
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Please cite this article as: Ilkovska B, Kotevska-Trifunova B, Ilkovski F. Anemia in Pregnancy, Study in Bitola, North Macedonia. J of IMAB. 2025 Jul-Sep;31(3):6428-6432. [Crossref - 10.5272/jimab.2025313.6428]
Correspondence to: Biljana llkovska, University St. Kliment Ohridski Bitola, Higher Medical School Bitola, Department of laboratory diagnostics, PHO Clinical hospital dr. Trifun Panovski Bitola; St. Dimce Lahcanski Br.29., Bitola, Macedonia; E-mail: drbiljanailkovska@yahoo.com
REFERENCES:
1. Araujo Costa E, de Paula Ayres-Silva J. Global profile of anemia during pregnancy versus country income overview: 19 years estimative (2000-2019). Ann Hematol. 2023 Aug;102(8):2025-2031. [PubMed]
2. Mbowe F, Darboe KS, Sanyang AM, Barrow A. Prevalence and determinants of anemia among pregnant women attending maternal and child health clinics at Sukuta Health Center, The Gambia: An institutional-based cross-sectional study. Womens Health (Lond). 2025 Jan-Dec;21:17455057251338380. [PubMed]
3. Shi H, Chen L, Wang Y, Sun M, Guo Y, Ma S, et al. Severity of Anemia During Pregnancy and Adverse Maternal and Fetal Outcomes. JAMA Netw Open. 2022 Feb 1;5(2):e2147046. [PubMed]
4. The Global Health Observatory. Anaemia in women of reproductive age (aged 15-49), prevalence (%), by pregnancy status. WHO. 2023. [Internet
5. Stephen G, Mgongo M, Hussein Hashim T, Katanga J, Stray-Pedersen B, Msuya SE. Anaemia in Pregnancy: Prevalence, Risk Factors, and Adverse Perinatal Outcomes in Northern Tanzania. Anemia. 2018 May 2;2018:1846280. [PubMed ]
6. Wang R, Xu S, Hao X, Jin X, Pan D, Xia H, et al. Anemia during pregnancy and adverse pregnancy outcomes: a systematic review and meta-analysis of cohort studies. Front Glob Womens Health. 2025 Jan 31;6:1502585. [Crossref]
7. Allen LH. Anemia and iron deficiency: effects on pregnancy outcome. Am J Clin Nutr. 2000 May;71(5 Suppl):1280S-4S. [PubMed]
8. Mbule MA, Byaruhanga YB, Kabahenda M, Lubowa A. Determinants of anaemia among pregnant women in rural Uganda. Rural Remote Health. 2013 Apr-Jun;13(2):2259. [PubMed]
9. Breymann C, Bian XM, Blanco-Capito LR, Chong C, Mahmud G, Rehman R. Expert recommendations for the diagnosis and treatment of iron-deficiency anemia during pregnancy and the postpartum period in the Asia-Pacific region. J Perinat Med. 2011 Mar;39(2):113-21. [PubMed]
10. Black RE, Victora CG, Walker SP, Bhutta ZA, Christian P, de Onis M, et al. Maternal and Child Nutrition Study Group. Maternal and child undernutrition and overweight in low-income and middle-income countries. Lancet. 2013 Aug 3;382(9890):427-451. [PubMed]
11. Rahman MM, Abe SK, Rahman MS, Kanda M, Narita S, Bilano V, et al. Maternal anemia and risk of adverse birth and health outcomes in low- and middle-income countries: systematic review and meta-analysis. Am J Clin Nutr. 2016 Feb;103(2):495-504. [PubMed]
12. Kamau MW, Mirie W, Kimani S. Compliance with Iron and folic acid supplementation (IFAS) and associated factors among pregnant women: results from a cross-sectional study in Kiambu County, Kenya. BMC Public Health. 2018 May 2;18(1):580. [Pubmed]
13. Karami M, Chaleshgar M, Salari N, Akbari H, Mohammadi M. Global Prevalence of Anemia in Pregnant Women: A Comprehensive Systematic Review and Meta-Analysis. Matern Child Health J. 2022 Jul;26(7):1473-1487. [PubMed]
14. Geta TG, Gebremedhin S, Omigbodun AO. Prevalence and predictors of anemia among pregnant women in Ethiopia: Systematic review and meta-analysis. PLoS ONE. 2022 Jul 27;17(7):e0267005. [PubMed]
15. Melkamu Z, Bereke T, Gebretsadik GG, Lema GK, Weldu AH, Beyene MH, et al. Anemia and its determinants among non-pregnant women of childbearing age at Tsirae Wonberta district, Tigray, Ethiopia, 2020: a community based cross sectional study. BMC Public Health. 2025 Mar 27;25(1):1169. [PubMed]
16. Erna EW, Umu Q. The correlation of maternal age and gestational age with anemia in pregnant women at puskesmas mraurek, tban, east Java Indonesia. Int J Midwifery Res. 2021 Jul;1(1):1-8. [Crossref]
17. Katsarou A, Pantopoulos K. Basics and principles of cellular and systemic iron homeostasis. Mol Aspects Med. 2020 Oct;75:100866. [PubMed]
18. Nicholson WK, Silverstein M, Wong JB, Chelmow D, Coker TR, Davis EM, et al. Screening and Supplementation for Iron Deficiency and Iron Deficiency Anemia During Pregnancy: US Preventive Services Task Force Recommendation Statement. JAMA. 2024 Sep 17;332(11):906-913. [PubMed]
Received: 07 February 2025
Published online: 02 Septtember 2025
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