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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2025, vol. 31, issue3
Subject Area: Medicine
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DOI: 10.5272/jimab.2025313.6484
Published online: 26 September 2025
Original article
J of IMAB. 2025 Jul-Sep;31(3):6484-6487
ANTIBIOTIC RESISTANCE IN COMPLICATED URINARY TRACT INFECTIONS
Boyan Lazarov
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Department of Urology, Faculty of Medicine, Medical University - Varna, Clinic of Urology, MHAT "Sveta Anna - Varna", Bulgaria.
ABSTRACT:
Purpose: Complicated urinary tract infections are those that are assumed to be more difficult to treat due to factors related to the host or specific anatomical or functional abnormalities related to the urinary tract. Because of the widespread antibiotic resistance in these cases, we tried to create an algorithm for the empirical treatment of such infections.
Material/Methods: The object of the study were 69 patients treated at the Urology Clinic of the "St. Anna-Varna" Hospital for a period of 1 year.
Results: 18 of the patients had no previous urological problems. In them, the most common causative agent was Escherichia coli (44.4%) - with good sensitivity to carbapenems, gentamicin, sulperazone. 51 patients had previous urological problems, and here, the share of enterococci (27.3%) increased. These bacteria had good sensitivity to aminopenicillins and vancomycin.
Conclusions: As a practical tip, we recommend Gram-staining of the urine 24th hour after taking the urine culture and changing the antibiotic if necessary, depending on whether the bacteria found are gram-negative or gram-positive.
Keywords: Aminopenicillins, carbapenems, aminoglucoside antibiotics, fluoroquinolones,
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Please cite this article as: Lazarov B. Antibiotic resistance in complicated urinary tract infections. J of IMAB. 2025 Jul-Sep;31(3):6484-6487. [Crossref - 10.5272/jimab.2025313.6484]
Correspondence to: Boyan Lazarov, Multiprofile Hospital for Active Treatment "Sveta Anna-Varna"- Clinic of urology, department of urology, Medical University-Varna; 100, Tzar Osvoboditel Blvd., Varna, 9000, Bulgaria; E-mail: boyanlazarov@yahoo.com
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Received: 14 January 2025
Published online: 26 Septtember 2025