Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN:
1312-773X (Online)
Issue:
2026, vol. 32, issue3
Subject Area:
Dental Medicine
-
DOI:
10.5272/jimab.2026323.7119
Published online: 28 September 2026
Review article
J of IMAB. 2026 Jul-Sep;32(3):7119-7123
RISK FACTORS FOR THE DEVELOPMENT OF SECONDARY CARIOUS LESIONS (SCLS) IN PRIMARY DENTITION- A REVIEW
Viktoriya Gateva


, Natalia Gateva-Grancharova
,
Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria.
ABSTRACT:
Secondary carious lesions (SCLs) are the main cause for failure of restorations and pose challenges in primary dentition due to the anatomical and physiological characteristics of the primary teeth. The objective of this article is to synthesize the information about the risk factors involved in the formation of SCLs in primary teeth. Material-related risk factors include the increased biofilm formation on composites, surface and chemical properties, residual monomer release, polymerization shrinkage, and biodegradation. The risk factors related to the patients are overall caries risk, oral-hygiene behaviors, diet, existing caries burden, and socioeconomic status. Operator-related factors are the moisture control, strict adherence to adhesive protocols, and quality of finishing. Cavity-related risks are highest for Class II restorations, particularly at gingival margins and proximal cervical areas of primary molars. The diagnosis is challenging because visual-tactile methods underdetect early and approximal lesions, bitewing radiography remains imperfect, and newer, modern technologies are promising yet not routine. Prevention must therefore be multifactorial, combining individualized risk assessment, optimal material selection, meticulous technique, biofilm management, and tailored recall. Continued pediatric-focused prospective research is needed to refine evidence-based strategies.
Keywords: secondary caries lesions (SCLs), primary dentition, pediatric dentistry, composite restorations, risk factors, , fluoride release, diagnosis, prevention,
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Please cite this article as: Gateva V, Gateva-Grancharova N. Risk factors for the development of secondary carious lesions (SCLs) in primary dentition- a review. J of IMAB. 2026 Jul-Sep;32(3):7119-7123. [Crossref - 10.5272/jimab.2026323.7119]
Correspondence to: Viktoriya Velizarova Gateva, Department of Pediatric dentistry, Faculty of Dental medicine, Medical University Sofia; 1, Georgi Sofiyski Str., Sofia, Bulgaria. E-mail: v.gateva@fdm.mu-sofia.bg
REFERENCES:
1. Brouwer F, Askar H, Paris S, Schwendicke F. Detecting Secondary Caries Lesions: A Systematic Review and Meta-analysis. J Dent Res. 2016 Feb;95(2):143-51. [PubMed]
2. Lima FG, Romano AR, Correa MB, Demarco FF. Influence of microleakage, surface roughness and biofilm control on secondary caries formation around composite resin restorations: an in situ evaluation. J Appl Oral Sci. 2009 Jan-Feb;17(1):61-5. [PubMed]
3. De Menezes Oliveira MA, Torres CP, Gomes-Silva JM, Chinelatti MA, De Menezes FC, Palma-Dibb RG, et al. Microstructure and mineral composition of dental enamel of permanent and deciduous teeth. Microsc Res Tech. 2010 May;73(5):572-7. [PubMed]
4. Peneva M, Kabakchieva R, Rashkova M, Tzolova E, Gateva N, Doichinova L, Jegova G. Clinics of Pediatric Dentistry. In: Textbook of Pediatric Dentistry. Sofia: Bedemot; 2018.
5. Fejerskov O, Kidd EAM, Nyvad B, Bælum V. (Eds.) Dental Caries: The Disease and its Clinical Management. 2 edit. Blackwell Publishing. 2008. 616 p. [Internet]
6. Käkilehto T, Välimäki S, Tjäderhane L, Vähänikkilä H, Salo S, Anttonen V. Survival of primary molar restorations in four birth cohorts-A retrospective, practice-based study. Acta Odontol Scand. 2013 Nov;71(6):1418-22. [PubMed]
7. Mjör IA. Clinical diagnosis of recurrent caries. J Am Dent Assoc. 2005 Oct;136(10):1426-33. [PubMed]
8. Metz I, Rothmaier K, Pitchika V, Crispin A, Hickel R, Garcia-Godoy F, et al. Risk factors for secondary caries in direct composite restorations in primary teeth. Int J Paediatr Dent. 2015 Nov;25(6):451-61. [PubMed]
9. Jokstad A. Secondary caries and microleakage. Dent Mater. 2016 Jan;32(1):11-25. [PubMed]
10. Nedeljkovic I, De Munck J, Vanloy A, Declerck D, Lambrechts P, Peumans M, et al. Secondary caries: prevalence, characteristics, and approach. Clin Oral Investig. 2020 Feb;24(2):683-691. [PubMed]
11. Nedeljkovic I, Van Landuyt KL. Chapter: Secondary Caries. In: Dental Composite Materials for Direct Restorations. Miletic V. (eds) Springer, Cham. 2018, pp.235-243. [Crossref]
12. Hickel R, Kaaden C, Paschos E, Buerkle V, Garcнa-Godoy F, Manhart J. Longevity of occlusally-stressed restorations in posterior primary teeth. Am J Dent. 2005 Jun;18(3):198-211. [PubMed]
13. Nedeljkovic I, Teughels W, De Munck J, Van Meerbeek B, Van Landuyt KL. Is secondary caries with composites a material-based problem? Dent Mater. 2015 Nov;31(11):e247-77. [PubMed]
14. Kim H, Lee J, Kim H, Park H. Surface Roughness and Cariogenic Microbial Adhesion after Polishing of Smart Chromatic Technology-based Composite Resin. J Korean Acad Pediatr Dent. 2023;50(1):65-74. [Crossref]
15. Mei L, Busscher HJ, van der Mei HC, Chen Y, de Vries J, Ren Y. Oral bacterial adhesion forces to biomaterial surfaces constituting the bracket-adhesive-enamel junction in orthodontic treatment. Eur J Oral Sci. 2009 Aug;117(4):419-26. [PubMed]
16. Yamamoto K, Ohashi S, Taki E, Hirata K. Adherence of oral streptococci to composite resin of varying surface roughness. Dent Mater J. 1996 Dec;15(2):201-4. [PubMed]
17. Shahal Y, Steinberg D, Hirschfeld Z, Bronshteyn M, Kopolovic K. In vitro bacterial adherence onto pellicle-coated aesthetic restorative materials. J Oral Rehabil. 1998 Jan;25(1):52-8. [PubMed]
18. Barutçugil Ç, Tayfun D, Çetin Tuncer N, Dündar A. Bacterial adhesion and surface properties of computer-aided design-computer-aided manufacturing restorative materials. J Oral Sci. 2024 Jul 16;66(3):157-162. [PubMed]
19. Staszczyk M, Kościelniak D, Krzyściak W, Jamka-Kasprzyk M, Kołodziej I, Kępisty M, et al. In vitro cariogenic model of biofilm formation on selected dental materials – pilot study. Nowa Stomatol. 2023 Dec;28(4):143-151. [Internet]
20. Wang Y, Du X, Jia Y, Qin L, Liu F, Cai Y, Wang S. Recent progress in antimicrobial strategies of controlled-release nanomaterials for secondary caries. Front Cell Infect Microbiol. 2025 Oct 1;15:1669643. [PubMed]
21. Elgezawi M, Haridy R, Abdalla MA, Heck K, Draenert M, Kaisarly D. Current Strategies to Control Recurrent and Residual Caries with Resin Composite Restorations: Operator- and Material-Related Factors. J Clin Med. 2022 Nov 7;11(21):6591. [PubMed]
22. Kharib AMM. Literature review of the relationship between secondary caries and the restoration gap size. Open J Clin Med Case Rep. 2024; 2251. [Crossref]
23. Askar H, Krois J, Gцstemeyer G, Bottenberg P, Zero D, Banerjee A, et al. Secondary caries: what is it, and how it can be controlled, detected, and managed? Clin Oral Investig. 2020 May;24(5):1869-1876. [PubMed]
24. van de Sande FH, Collares K, Correa MB, Cenci MS, Demarco FF, Opdam N. Restoration Survival: Revisiting Patients’ Risk Factors Through a Systematic Literature Review. Oper Dent. 2016 Sep;41(S7):S7-S26. [PubMed]
25. Metz I, Rothmaier K, Pitchika V, Crispin A, Hickel R, Garcia-Godoy F, et al. Risk factors for secondary caries in direct composite restorations in primary teeth. Int J Paediatr Dent. 2015 Nov;25(6):451-61. [PubMed]
26. Demarco FF, Corrкa MB, Cenci MS, Moraes RR, Opdam NJ. Longevity of posterior composite restorations: not only a matter of materials. Dent Mater. 2012 Jan;28(1):87-101. [PubMed]
27. Nedeljkovic I, De Munck J, Vanloy A, Declerck D, Lambrechts P, Peumans M, et al. Secondary caries: prevalence, characteristics, and approach. Clin Oral Investig. 2020 Feb;24(2):683-691. [PubMed]
28. Stoleriu S, Andrian S, Pancu G, Nica I, Iovan G. The influence of saliva on Gingival marginal microleakage of class II cavities when using Universal Bonding Agent in Direct Composite Restoration. IOP Conf Ser: Mater Sc. Eng. 2018;374:012090. [Crossref]
29. Walia T, Kirthiga M, Brigi C, Muthu MS, Odeh R, Pakash Mathur V, et al. Interproximal contact areas of primary molars based on OXIS classification - a two centre cross sectional study. Wellcome Open Res. 2021 Feb 3;5:285. [Crossref]
30. Muthu MS, Kirthiga M, Lee JC, Kayalvizhi G, Mathur VP, Kandaswamy D, et al. OXIS Contacts as a Risk Factor for Approximal Caries: A Retrospective Cohort Study. Pediatr Dent. 2021 Jul 15;43(4):296-300. [PubMed]
31. Mosavat F, Ahmadi E, Aghajani F, Ramezani S. Effect of composite radiopacity and margin location of the restoration on the diagnosis of secondary caries. Braz Dent J. 2024 Mar 22;35:e245583. [PubMed]
32. Adly AM, Ibrahim SH, El-Zoghbi AF. Clinical validity of fluorescence-based devices versus visual-tactile method in detection of secondary caries around resin composite restorations: diagnostic accuracy study. BDJ Open. 2025 Jan 6;11(1):2. [PubMed]
33. Rodrigues JA, Neuhaus KW, Stich I, Hug H, Seemann R, Lussi A. In Vitro Detection of Secondary Caries Associated with Composite Restorations on Approximal Surfaces Using Laser Fluorescence. Oper Dent. 2010 Sep-Oct;35(5):564-71. [PubMed]
34. Shahidi S, Zadeh NK, Sharafeddin F, Shahab S, Bahrampour E, Hamedani S. An in vitro comparison of diagnostic accuracy of cone beam computed tomography and phosphor storage plate to detect simulated occlusal secondary caries under amalgam restoration. Dent Res J (Isfahan). 2015 Mar-Apr;12(2):161-6. [PubMed]
35. Ghoncheh Z, Zonouzy Z, Kiomarsi N, Kharazifar MJ, Chiniforush N. In Vitro Comparison of Diagnostic Accuracy of DIAGNOdent and Digital Radiography for Detection of Secondary Proximal Caries Adjacent to Composite Restorations. J Lasers Med Sci. 2017 Fall;8(4):172-176. [PubMed]
36. Santos MJMC, Zare E, McDermott P, Santos Junior GC. Multifactorial Contributors to the Longevity of Dental Restorations: An Integrated Review of Related Factors. Dent J (Basel). 2024 Sep 12;12(9):291. [PubMed]
Received: 06 October 2025
Published online: 28 September 2026
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