back to 2005, vol. 11, b. 1
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2005, vol. 11, book 1
Subject Collection: Medicine
Page: 13-14
DOI: 10.5272/jimab.2005111.13
Online date: October 19, 2005

J of IMAB 2005; 11(1):13-14
Maria Atanasova, Galya I. Gancheva, Penka Ilieva, Chrisima Tzvetanova, Iskra Simova
Department of Infectious Diseases, Epidemiology, Parasitology and Tropical Medicine,
Medical University, Pleven, Bulgaria

The research includes 84 patients with leptospirosis treated in Clinic at Infectious Diseases – Pleven. Mild course in 52,38%, moderate in 19,05%, and severe in 28,57% are established. Serum amylase level has been investigated in 37 cases. Increased rates are measured in 41,67% of mild cases (av. 279 U/L), in 25% of moderate cases (av. 290 U/L), and in 88,24% of severe cases(av. 937 U/L). Significant difference between serum amylase levels of mild and severe cases is established (p < 0,02). Presumably immunological mechanisms of damage by participation of interleukins (IL1, IL6, IL8) and tumor necrosis factor (TNF-β) are in the base of increased serum amylase level in leptospirosis. The functional changes of pancreas in leptospirosis are not fully clear and further research is needed.

Key words: leptospirosis, pancreas, serum amylase, interleukins.

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Please cite this article as: Atanasova M, Gancheva G, Ilieva P, Tzvetanova Chr, Simova I. PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS. J of IMAB 2005; 11(1):13-14; DOI: 10.5272/jimab.2005111.13

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Please cite this article as: Atanasova M, Gancheva G, Ilieva P, Tzvetanova Chr, Simova I. PANCREATIC INVOLVEMENT IN LEPTOSPIROSIS. J of IMAB 2005; 11(1):13-14; DOI: 10.5272/jimab.2005101.13

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