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Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312-773X (Online)
Issue: Volume 15, book 1, 2009
Subject Collection: Medicine
Page: 95 - 97
DOI: 10.5272/jimab.1512009_95
Online date:Feb. 23, 2010
Infections in urinary tract of patients with haematological malignancies undergoing antineoplastic therapy
S. Tancheva1, I. Micheva2, I. Marinova1, B. Bojchev1, M. Marinov3, K. Nenov4, R. Radev3
1 Department of Clinical Laboratory , 2 Department of Internal Medicine-Haematology Division, University Hospital, Medical University – Varna, 3Department of Preclinical and Clinical Medical Sciences, Medical University – Varna, 4Department of Internal Medicine-Nephrology and Haemodialysis Division, University Hospital, Medical University – Varna, Bulgaria.
ABSTRACT: The treatment of the malignant diseases requires the use of combination chemotherapy in multiple cycles administered to achieve adequate tumor cell kill without life-threatening toxicity or the development of tumor cell resistance. Patients and methods:72 patients (48 women and 24 men, median age – 47, from 24 to 71years with urinary tract infections (UTI), hospitalized in the Clinic of Hematology for the period January 2006-May 2008. Urinalysis: microscopic examination – white blood cells (WBC), bacteria; urine culture; sensitivities of culture. Blood tests: urea (kinetic UV test ), creatinin (Jaffe kinetic), CRP (immunoturbidimetric method), blood culture, sensitivities of culture. Results and conclusions:The urinary tract infections are a common complication during the combination chemotherapy patients with hematological malignancies. For the period 2006-2008, 72 patients undergoing combination chemotherapy were diagnosed with UTI.
Key words: urinary tract infections; antineoplastic therapy; Beta-2 microglobulin.
Page: 95-97; FULL TEXT PDF (184 KB)