back to 2010, vol. 16, b. 3

Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2010, vol. 16, book 3
Subject Collection: Medicine
Page: 51 - 53
DOI: 10.5272/jimab.1632010_51
Online date: January 28, 2010

LOCALIZED FORM OF LYMPHOMATOID PAPULOSIS, EVALUATING ING IN T-CELL LYMPHOMA – Case Report
S. Shtilionova1, P. Drumeva1, M. BalabanovaІ2, I. Krasnaliev3 
1) Department of dermatology and venereology, Medical University - Varna
2) Department of dermatology and venereology, Medical University - Sofia
3) Department of pathology, Medical University - Varna, Bulgaria

ABSTRACT:
Lymphomatoid papulosis is presented by sponta­neously regressing cutaneous infiltrates, that microscopically resemble a lymphomas and may evolve into Hodgkin or non- Hodgkin malignant lymphoma.
We present a case of Lymphomatoid papulosis in a 64 years old male, who complains from reddish non painful papules, localized symmetrically on the back and lateral zone of the legs.
The patient was treated for 10 weeks with low dose of methotrexat (15 mg per week) with good clinical result.
One year after treatment interruption the same patient had a similar clinical changes and hystochemical signs for development of T-cell lymphoma.

Key words:  Lymphomatoid papulosis, T-cell lymphoma, hystopathology, immunohistochemistry .

Page: 51-53; FULL TEXT PDF (369 KB) Abstract

References:
1. Burg G, Kerl H, Schmoeckel C. Differentiation between malignant B-cell lymphomas and pseudolymphomas of the skin. J Dermatol Oncol 1984; 10: 271-275. [PubMed]
2. Burg G, Braun-Falco O. Cutaneous pseudolymphomas. In: Cutaneous lymphomas. Berlin: Springer-Verlag, 1983, 415-464.
3. Duncan SC, Evans HL, Winkelmann RK. Large cell lymphocytoma. Arch Dermatol. 1980; Oct;116(10): 1142-1146. [PubMed]
4. Dorfman RF, Warnke R. Lymphadenopathy simulating the malignant lymphomas. Hum Pathol 1974; 5(5) 519-50 [PubMed]
5. Englich JC, Smith NP, Wilson Jones E, Winkelmann RK. Large cell lymphocytoma [abstract]. J Cutan Pathol 1986; 13: 441.
6. Kerl H, Ackerman AB. Inflammatory diseases that simulate lymphomas: cutaneous pseudolymphomas. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF (editors). Dermatology in general medicine, 4th ed. New York: McGrew-Hill, 1993, 1315-1327.
7. Landa N, Zelickson BD, Peters MS, et al. Cutaneous lymphoma versus pseudolymphoma: gene rearrangement studies of 21 cases with clinicopathologic correlation [Abstr.]. J Invest Dermatol

back to Online Journal