back to 2010, vol. 16, b. 4

Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2010, Volume 16, book 4,
DOI: 10.5272/jimab.1642010_18-20
Subject Collection:Oral and Dental Medicine
Page: 18 - 20
Online date: Oct 19, 2010

EFFECTIVNESS OF TARGET ANTIMICROBIAL THERAPY OF SEVERE CHRONIC PERIODONTITIS
PART I: REDUCTION OF GINGIVAL INFLAMATION AND ACTIVE PERIODONTAL DISEASE SITES
Kamen Kotsilkov, Christina Popova, V. Dosseva
Department of Periodontology, Faculty of Dental Medicine,
Medical University - Sofia, Bulgaria

ABSTRACT:
The correlation between recurrent bleeding on probing and the progression of periodontal destruction is suggested in many studies. One of the main goals of the periodontal treatment is the achievement of good control of the gingival inflammation and the reduction of the active periodontal sites.
Aim: Evaluation of the effectiveness of treatment of severe chronic periodontitis with additional target antibiotic administration in comparison with the therapy with adjunctive antimicrobial combination amoxicillin + metronidazole and conventional mechanical periodontal treatment regarding the achieved control of the gingival inflammation and BoP.
Results:  Significant reduction of the gingival bleeding and the BoP is achieved in all groups. In the group with target antibiotic administration the final mean values of the GB (gingival bleeding) and BoP (bleeding on probing) are the lowest and could suggest a low risk for progression of the periodontal disease.

Key words: gingival inflammation, periodontitis, periodontal disease progression, risk assessment.

Page: 18-20; FULL TEXT PDF (216 KB) Abstract

REFERENCES:
1. Armitage GC.  The complete periodontal examination. Periodontol 2000, 2004; 34: 22-33.[ PubMed ]
2. Dahlen G. Role of suspected periodontopathogens in microbiological monitoring in periodontitis. Adv Dent Res 1993; 7(2): 163-174.
3. Djemileva, T. Periodontal diseases. Azer Sofia, 1999, 367p.
4. Djemileva-Konova, T. Clinical and experimental data for the influence of the dental plaque upon gingival tissue. Diss., Sofia, Faculty of Stomatology, 1976, 250p.
5. Haffajee AD., Cugini MA., Dibart S., Smith C., Kent RL., Socransky SS. The effect of SRP on the clinical and micro­biological parameters of periodontal disease. J Clin Periodontol 1997; 24: 324- 334.
6. Haffajee AD., Socransky SS. Microbial etiological agents of destructive periodontal diseases. Periodontol 2000, 1994 Jun; 5: 78-111. [ PubMed ]
7. Nishihara T., Koseki T. Microbial etiology of periodontitis. Periodontology 2000, 2004; 36: 14–26.
8. Persson GR. Site-based versus subject-based periodontal diagnosis. Periodontology 2000, 2005; 39: 145–163.[ CrossRef ]
9. Popova Chr. Control and prevention of gingival inflammation by chemical inhibition of dental plaque. Diss., Sofia, Faculty of Stomatology, 1998, 187p. (in Bulgarian)
10. Socransky SS., Haffajee AD. Periodontal microbial ecology. Periodontology 2000, 2005; 38: 135–187.
11. Socransky SS., Haffajee AD., Cugini MA., Smith C., Kent RL. Microbial complexes in subgingival plaque. J Clin Periodontol 1998; 25(2):134-144.
12. Winkel EG, van Winkelhoff AJ, Timmerman MF, Van der Velden U, van der Weijden GA. Amoxicillin plus metronidazole in the treatment of adult periodontitis patients. A double-blind placebo-controlled study. J Clin Periodontol 2001;28(4):296-305.[ PubMed ]

back to Online Journal