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Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2010, Volume 16, book 4,
DOI: 10.5272/jimab.1642010_21-23
Subject Collection:Oral and Dental Medicine
Page: 21 - 23
Online date: Oct 19, 2010
EFFECTIVNESS OF TARGET ANTIMICROBIAL THERAPY OF SEVERE CHRONIC PERIODONTITIS
PART II: PREVALENCE OF RESIDUAL POCKETS
Kamen Kotsilkov, Christina Popova,
Department of Periodontology, Faculty of Dental Medicine,
Medical University - Sofia, Bulgaria
ABSTRACT:
Comprehensive treatment of periodontitis is very different from the treatment of most bacterial infections. While periodontitis is traditionally considered a bacterial infection, many variables influence treatment outcomes.
The reduction of the probing depth of the periodontal pockets is one of the main criteria for the success of the periodontal treatment. The prevalence of the residual pockets with probing depth greater than 4 mm determines the risk of disease progression. The reduction of the periodontal sites with PD above 7mm with non-surgical periodontal treatment could limit the necessity of periodontal surgery.
Aim: Evaluation of the effectiveness of treatment of severe chronic periodontitis with additional target antibiotic administration in comparison with the therapy with adjunctive antimicrobial combination amoxicillin+metronidazole and conventional mechanical periodontal treatment regarding the prevalence and the achieved mean reduction of PD of periodontal pockets with initial PPD below 3mm, from 3 to 5mm, from 5-7mm and above 7mm.
Results: In all study groups a reduction of the mean PD has been achieved. The prevalence of periodontal sites with PD above 7mm after therapy is the lowest in the group with target antibiotic administration. These results advocate the effectiveness of the target adjunctive antimicrobial treatment in order to limit the extent of the surgical procedures in the therapy of the periodontal disease.
Key words: periodontitis, adjunctive antibiotic therapy, target antibiotic administration, PPD reduction, long-term maintenance.
Page: 21-23; FULL TEXT PDF (619 KB) Abstract
REFERENCES:
1. Brochut PF., Marin I., Baehni P., Mombelli A. Predictive value of clinical and microbiological parameters for the treatment outcome of scaling and root planning. J Clin Periodontol. 2005 Jul; 32(7): 695-701. [PubMed]
2. Haffajee AD., Cugini MA., Dibart S., Smith C., Kent RL., Socransky SS. The effect of SRP on the clinical and microbiological parameters of periodontal disease. J Clin Periodontol 1997; 24: 324- 334.
3. Haffajee AD., Socransky SS., Feres M., Himenez-Fyvie LA. Plaque microbiology in health and disease. In: Newman HS. Wilson M. Dental plaque revised: oral biofilms in health and diseases. Cardiff school of biosciences, 1999: 255-282.
4. Holt SC., Ebersole JL. Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia: the _red complex_, a prototype polybacterial pathogenic consortium in periodontitis. Periodontology 2000, 2005; 38: 72–122.[ CrossRef ] [ PubMed ]
5. Mombelli A., Casagni F., Madianos P.N. Can presence or absence of periodontal pathogens distinguish between subjects with chronic and aggressive periodontitis? A systematic review. J Clin Periodontol 2002; 29(Suppl.3): 10-21.[ PubMed ]
6. Popova Chr., K. Kotsilkov. Effectiveness of the additional antimicrobial treatment in comparison with mechanical cause-related therapy of chronic periodontitis. Zabolekarski pregled 1/2007 70,71p.
7. Slots J. Bacterial specifity in adult periodontitis. J Clin Periodontol 1986; 13: 912-917.
8. Socransky SS., Haffajee AD. Dental biofilms: difficult therapeutic targets. Periodontology 2000, 2002; 28: 12–55.[ CrossRef ] [ PubMed ]
9. Socransky SS., Haffajee AD. Periodontal microbial ecology. Periodontology 2000, 2005; 38: 135–187. [CrossRef ]
10. Van Winkelhoff A.J., Rams T. & Slots J. Systemic antibiotic therapy in periodontitis.Periodontology 2000, 1996: 10,45-78
11. Walker C. B., Karpinia K. & Baehni P. Chemotherapeutics: antibiotics and other antimicrobials. Periodontology 2000; 36, 2004, 146–165 [ CrossRef ]
12. Yano-Higuchi K., Takamatsu N., He T., Umeda M., Ishikawa I. Prevalence of Bacteroides forsytus, Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in subgingival microflora of Japanese patients with adult and rapidly progressive periodontitis. J Clin Periodontol 2000; 27: 597- 602.